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Merck

SAB4504393

Sigma-Aldrich

Anti-phospho-eNOS (pSer1176) antibody produced in rabbit

affinity isolated antibody

Synonym(e):

Anti-ECNOS, Anti-eNOS

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About This Item

UNSPSC-Code:
12352203
NACRES:
NA.41

Biologische Quelle

rabbit

Konjugat

unconjugated

Antikörperform

affinity isolated antibody

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Form

buffered aqueous solution

Mol-Gew.

antigen 133 kDa

Speziesreaktivität

rat, human, mouse

Konzentration

~1 mg/mL

Methode(n)

ELISA: 1:20000
western blot: 1:500-1:1000

NCBI-Hinterlegungsnummer

UniProt-Hinterlegungsnummer

Versandbedingung

wet ice

Lagertemp.

−20°C

Posttranslationale Modifikation Target

phosphorylation (pSer1176)

Angaben zum Gen

human ... NOS3(4846)

Allgemeine Beschreibung

Nitric oxide synthase 3 (NOS3), also known as endothelial nitric oxide synthase (eNOS), is encoded by the gene mapped to human chromosome 7q35-36. The gene consists of 26 exons.

Immunogen

The antiserum was produced against synthesized peptide derived from human eNOS around the phosphorylation site of Ser1176.

Immunogen Range: 1144-1193

Biochem./physiol. Wirkung

Nitric oxide synthase 3 (NOS3) has been studied as a modulator of vascular function and is involved in the production of nitric oxide. Defects in the enzyme expression have been shown to be associated with coronary artery disease.

Leistungsmerkmale und Vorteile

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physikalische Form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Analysenzertifikate (COA)

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Die Dokumentenbibliothek aufrufen

Association between three eNOS polymorphisms and intracranial aneurysms risk: a meta-analysis.
Yang C, et al.
Medicine, 94(4) (2015)
Bing Yi et al.
Arteriosclerosis, thrombosis, and vascular biology, 35(10), 2153-2160 (2015-08-22)
Endothelial nitric oxide synthase (eNOS) is an important regulator of vascular function and its expression is regulated at post-transcriptional levels through a yet unknown mechanism. The purpose of this study is to elucidate the post-transcriptional factors regulating eNOS expression and
Marwa Ben Ali et al.
Genetic testing and molecular biomarkers, 19(4), 203-208 (2015-03-10)
Nitric oxide (NO), produced by the enzyme endothelial nitric oxide synthase (eNOS), has critical roles in the regulation of vascular homeostasis and prevention of atherogenesis by inhibiting leukocytes, platelet activation, and smooth muscle cell proliferation. There is strong experimental and
Zhaohui Fang et al.
Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society, 28(6), 683-691 (2020-06-20)
Medicinal plants act as an alternative source of anti-diabetic agents. Recently, Danzhi Jiangtang capsule (DJC) has been clinically used for treatment of diabetes, but the effect of DJC on diabetic macroangiopathy remained unclear. The present study investigates the therapeutic role
Lorraine Eley et al.
Disease models & mechanisms, 17(1) (2023-12-19)
eNOS (NOS3) is the enzyme that generates nitric oxide, a signalling molecule and regulator of vascular tone. Loss of eNOS function is associated with increased susceptibility to atherosclerosis, hypertension, thrombosis and stroke. Aortopathy and cardiac hypertrophy have also been found

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