Direkt zum Inhalt
Merck

SAB4502244

Sigma-Aldrich

Anti-CYTL1 antibody produced in rabbit

affinity isolated antibody

Synonym(e):

C4orf4, Cytokine-like protein 1, Protein C17

Anmeldenzur Ansicht organisationsspezifischer und vertraglich vereinbarter Preise


About This Item

UNSPSC-Code:
12352203
NACRES:
NA.41

Biologische Quelle

rabbit

Konjugat

unconjugated

Antikörperform

affinity isolated antibody

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Form

buffered aqueous solution

Mol-Gew.

antigen 15 kDa

Speziesreaktivität

human

Konzentration

~1 mg/mL

Methode(n)

ELISA: 1:40000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000

NCBI-Hinterlegungsnummer

UniProt-Hinterlegungsnummer

Versandbedingung

wet ice

Lagertemp.

−20°C

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... CYTL1(54360)

Allgemeine Beschreibung

Anti-CYTL1 antibody detects endogenous levels of total CYTL1 protein.
The CYTL1 (cytokine like 1) gene is mapped to human chromosome 4p16.2. The gene was first discovered in CD34(+) cells of the bone marrow and cord blood. The encoded protein is predominantly expressed in chondrocytes.

Immunogen

The antiserum was produced against synthesized peptide derived from human CYTL1.

Immunogen Range: 61-110

Biochem./physiol. Wirkung

In vitro studies reveal that Cytl1 (cytokine like 1) acts as an autocrine or paracrine regulatory factor in the process of cartilage formation. CYTL1, being homologous with IL-2 (interleukin-2), is considered as a potential cytokine that is involved in regulating immune responses. CYTL1 is known to be associated with the pathogenesis of rheumatoid arthritis and osteoarthritis.

Leistungsmerkmale und Vorteile

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physikalische Form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sie haben nicht das passende Produkt gefunden?  

Probieren Sie unser Produkt-Auswahlhilfe. aus.

Lagerklassenschlüssel

10 - Combustible liquids

WGK

nwg

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

Besitzen Sie dieses Produkt bereits?

In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Cytokine-like 1 Chemoattracts Monocytes/Macrophages via CCR2.
Wang X
Journal of Immunology, 196(10), 4090-4099 (2016)
Identification of CCR2-binding features in Cytl1 by a CCL2-like chemokine model.
Tomczak A
Proteins: Structure, Function, and Genetics, 79(4), 1277-1292 (2011)
Tanja Vukićević et al.
Journal of the American Society of Nephrology : JASN, 30(5), 795-810 (2019-04-17)
Arginine-vasopressin (AVP) binding to vasopressin V2 receptors promotes redistribution of the water channel aquaporin-2 (AQP2) from intracellular vesicles into the plasma membrane of renal collecting duct principal cells. This pathway fine-tunes renal water reabsorption and urinary concentration, and its perturbation
Corticotropin-Releasing Hormone Receptor 2 Gene Variants in Irritable Bowel Syndrome.
Komuro H
PLoS ONE, 11(1), 1-15 (2016)
Doris Schneller et al.
Circulation research, 124(2), 243-255 (2018-12-26)
Endothelial colony forming cells (ECFCs) or late blood outgrowth endothelial cells can be isolated from human cord or peripheral blood, display properties of endothelial progenitors, home into ischemic tissues and support neovascularization in ischemic disease models. To assess the functions

Unser Team von Wissenschaftlern verfügt über Erfahrung in allen Forschungsbereichen einschließlich Life Science, Materialwissenschaften, chemischer Synthese, Chromatographie, Analytik und vielen mehr..

Setzen Sie sich mit dem technischen Dienst in Verbindung.