SAB4300151

Anti-phospho-EGFR (pThr⁶⁷⁸) antibody produced in rabbit

affinity isolated antibody

• Synonym(e): Anti-ERBB antibody produced in rabbit, Anti-ERBB1 antibody produced in rabbit, Anti-HER1 antibody produced in rabbit, Anti-PIG61 antibody produced in rabbit, Anti-epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) antibody produced in rabbit
• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Konjugat: unconjugated
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous solution
• Mol-Gew.: ~175 kDa
• Speziesreaktivität: mouse, human, rat
• Konzentration: 1 mg/mL
• Methode(n): western blot: 1:500-1:1000
• Isotyp: IgG
• Immunogene Sequenz: (K-R-TP-L-R)
• NCBI-Hinterlegungsnummer: NP_005219.2
• UniProt-Hinterlegungsnummer: P00533
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: phosphorylation (pThr678)
• Angaben zum Gen: human ... EGFR(1956)

Beschreibung

Immunogen

Peptide sequence around phosphorylation site of threonine 678 (K-R-T(p)-L-R), according to the protein EGFR.

Leistungsmerkmale und Vorteile

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Zielbeschreibung

Receptor for EGF, but also for other members of the EGF family, as TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentiation. Phosphorylates MUC1 in breast cancer cells and increases the interaction of MUC1 with SRC and CTNNB1/beta-catenin.

Physikalische Form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable