SAB4300071

Anti-phospho-CAV1 (pTyr¹⁴) antibody produced in rabbit

affinity isolated antibody

• Synonym(e): Anti-BSCL3 antibody produced in rabbit, Anti-CAV antibody produced in rabbit, Anti-CGL3 antibody produced in rabbit, Anti-MSTP085 antibody produced in rabbit, Anti-caveolin 1, caveolae protein, 22kDa antibody produced in rabbit
• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Konjugat: unconjugated
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous solution
• Mol-Gew.: ~24 kDa
• Speziesreaktivität: mouse, rat, human
• Konzentration: 1 mg/mL
• Methode(n): indirect immunofluorescence: 1:100-1:200; western blot: 1:500-1:1000
• Isotyp: IgG
• Immunogene Sequenz: (H-L-YP-T-V)
• NCBI-Hinterlegungsnummer: NP_001166366.1
• UniProt-Hinterlegungsnummer: Q03135
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: phosphorylation (pTyr14)
• Angaben zum Gen: human ... CAV1(857)

Beschreibung

Immunogen

Peptide sequence around phosphorylation site of tyrosine 14 (H-L-Y(p)-T-V), according to the protein CAV1.

Leistungsmerkmale und Vorteile

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Zielbeschreibung

The scaffolding protein encoded by Caveolin-1 is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 MAP kinase cascade. CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. By using alternative initiation codons in the same reading frame, two isoforms (alpha and beta) are encoded by a single transcript from this gene.

Physikalische Form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable