SAB2700012

Anti-MIA3 (N-terminal) antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• Synonym(e): ARNT, FLJ21469, FLJ39207, MIA3
• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Konjugat: unconjugated
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous solution
• Speziesreaktivität: human
• Methode(n): immunofluorescence: suitable; immunohistochemistry: suitable; western blot: 500-3000
• NCBI-Hinterlegungsnummer: XP_496436
• UniProt-Hinterlegungsnummer: Q5JRA6
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Angaben zum Gen: human ... MIA3(375056)

Beschreibung

Immunogen

Recombinant fragment corresponding to a region within amino acids 1 and 150 of MIA3 according to XP_496436

Anwendung

Suggested starting dilutions are as follows: ICC/IF: 1:100-1:1000, IHC-P: 10 μg/mL, WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.

Biochem./physiol. Wirkung

Required for collagen VII (COL7A1) secretion by loading COL7A1 into transport carriers. May participate in cargo loading of COL7A1 at endoplasmic reticulum exit sites by binding to COPII coat subunits Sec23/24 and guiding SH3-bound COL7A1 into a growing carrier. Does not play a role in global protein secretion and is apparently specific to COL7A1 cargo loading. However, it may participate in secretion of other proteins in cells that do not secrete COL7A1.

Leistungsmerkmale und Vorteile

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Physikalische Form

0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable