SAB2501252

Anti-CLEC4C antibody produced in goat

affinity isolated antibody, buffered aqueous solution

• Synonym(e): Anti-BDCA2, Anti-CD303, Anti-CLECSF11, Anti-CLECSF7, C-type lectin domain family 4, member C
• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: goat
• Konjugat: unconjugated
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous solution
• Speziesreaktivität: human
• Methode(n): indirect ELISA: suitable; western blot: suitable
• UniProt-Hinterlegungsnummer: Q8WTT0
• Versandbedingung: dry ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... CLEC4C(170482)

Beschreibung

Allgemeine Beschreibung

C-type lectin domain family 4 member C (CLEC4C) is also known as blood dendritic cell antigen 2. It is expressed on plasmacytoid dendritic cells. CLEC4C is a type II transmembrane protein belonging to the C-type lectin (CTLs) superfamily. The protein consists of an extracellular carbohydrate recognition domain (CRD), a transmembrane region and a short cytoplasmic domain. The gene encoding CLEC4C is localized on human chromosome 12.

Immunogen

Peptide with sequence QSWTKSQKNCSV, from the Internal region of the protein sequence according to NP_569708.1; NP_987099.1.

Biochem./physiol. Wirkung

C-type lectin domain family 4 member C (CLEC4C) is involved in intracellular signal transduction through the transmembrane adaptor, FcεRγ. It inhibits the secretion of soluble TNF-related apoptosis-inducing ligand (TRAIL). CLEC4C may have a role in ligand internalization.

Leistungsmerkmale und Vorteile

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Physikalische Form

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 12 - Non Combustible Liquids
• WGK: WGK 2
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable