SAB1300730

Anti-Phospho-TEK-pY1113 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• Synonym(e): Anti-TEKT1, Anti-Tektin-1
• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100
• Konjugat: unconjugated
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous solution
• Speziesreaktivität: human
• Methode(n): dot blot: suitable; indirect ELISA: 1:1000
• NCBI-Hinterlegungsnummer: NP_444515
• UniProt-Hinterlegungsnummer: Q969V4
• Versandbedingung: dry ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: phosphorylation (pTyr113)
• Angaben zum Gen: human ... TEK(83659)

Beschreibung

Allgemeine Beschreibung

The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice, rats, and humans. This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats. The ligand for the receptor is angiopoietin-1. Defects in TEK are associated with inherited venous malformations; the TEK signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis. TEK is closely related to the TIE receptor tyrosine kinase.

Immunogen

TEK (NP_444515, 1096-1128)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y1113 of human TEK.

Physikalische Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: nwg
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable