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Merck

S1172

Sigma-Aldrich

Anti-Syntaxin 1 antibody produced in rabbit

IgG fraction of antiserum, lyophilized powder

Synonym(e):

Anti-GEFSP9, Anti-STX1B1, Anti-STX1B2

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About This Item

MDL-Nummer:
UNSPSC-Code:
12352203
NACRES:
NA.41

Biologische Quelle

rabbit

Qualitätsniveau

Konjugat

unconjugated

Antikörperform

IgG fraction of antiserum

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Form

lyophilized powder

Speziesreaktivität

mouse, rat

Methode(n)

immunohistochemistry: suitable using rat brain sections
western blot (chemiluminescent): 1:1,000 using rat brain membranes

UniProt-Hinterlegungsnummer

Lagertemp.

−20°C

Angaben zum Gen

Verwandte Kategorien

Allgemeine Beschreibung

Syntaxin 1 is a membrane protein. It is also known as HPC-1. Neurons express syntaxin 1A.

Immunogen

highly purified GST fusion protein with the residues 1-265 of rat syntaxin 1A (intracellular, N-terminal).

Anwendung

Anti-Syntaxin 1 antibody has been used in western blotting and immunohistochemistry.

Biochem./physiol. Wirkung

Syntaxin 1 (STX1A) may control exocytosis in synaptic vesicles. In retina, STX1A may help in the structural formation of the INL (inner nuclear layer) and OPL(outer plexiform layer). Deletion of STX1A in mice affects the functions of hypothalamic-pituitary-adrenal axis. It may participate in spinal nociceptive plasticity promoted by peripheral nerve injury.

Physikalische Form

After reconstitution, the antibody solution is phosphate buffered saline, pH 7.4, containing 1% BSA and 0.05% sodium azide.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Piktogramme

Exclamation mark

Signalwort

Warning

Gefahreneinstufungen

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Aquatic Chronic 3

Lagerklassenschlüssel

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)


Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Die Dokumentenbibliothek aufrufen

Impaired NGF/TrkA Signaling Causes Early AD-Linked Presynaptic Dysfunction in Cholinergic Primary Neurons
Latina V, et al.
Frontiers in Cellular Neuroscience, 11 (2017)
SNARE protein expression in synaptic terminals and astrocytes in the adult hippocampus: a comparative analysis
Schubert V, et al.
Glia, 59(10), 1472-1488 (2011)
Tiziana Cotrufo et al.
The European journal of neuroscience, 36(9), 3152-3164 (2012-09-06)
Directed cell migration and axonal guidance are essential steps in neural development that share many molecular mechanisms. The guidance of developing axons and migrating neurons is likely to depend on the precise control of plasmalemma turnover in selected regions of
Chronic exercise enhances insulin secretion ability of pancreatic islets without change in insulin content in non-diabetic rats
Tsuchiya M, et al.
Biochemical and Biophysical Research Communications, 430(2), 676-682 (2013)
Unusual retinal layer organization in HPC-1/syntaxin 1A knockout mice
Kaneko Y, et al.
Journal of Molecular Histology, 42(5), 483-489 (2011)

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