Direkt zum Inhalt
Merck
Alle Fotos(2)

Dokumente

RAB0205

Sigma-Aldrich

Human GDNF ELISA Kit

for serum, plasma, cell culture supernatant and urine

Anmeldenzur Ansicht organisationsspezifischer und vertraglich vereinbarter Preise
Alle Fotos(2)

About This Item

UNSPSC-Code:
41116158
NACRES:
NA.32

Speziesreaktivität

human

Verpackung

kit of 96 wells (12 strips x 8 wells)

Methode(n)

ELISA: suitable
capture ELISA: suitable

Aufnahme

sample type serum
sample type urine
sample type cell culture supernatant(s)
sample type plasma

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 4 pg/mL
standard curve range: 2.74-2000 pg/mL

Nachweisverfahren

colorimetric

Versandbedingung

wet ice

Lagertemp.

−20°C

Angaben zum Gen

human ... GDNF(2668)

Verwandte Kategorien

Allgemeine Beschreibung

Glial cell derived neurotrophic factor (GDNF) is encoded by the gene mapped to human chromosome 5p14.1−q13.3. It belongs to the transforming growth factor β (TGF-β) superfamily. GDNF is abundantly found in gliomas.

Immunogen

Recombinant Human GDNF

Anwendung

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Biochem./physiol. Wirkung

Glial cell derived neurotrophic factor (GDNF) is a neurotrophic factor involved in dopaminergic and neurodevelopment. It plays a vital role in self-renewal of stem cells. In addition, GDNF also facilitates differentiation of chained undifferentiated spermatogonia. GDNF with its receptors, activates various signaling pathways essential for maintaining cellular homeostasis. Mutated gene is associated with the development of schizophrenia. GDNF is a potential target for treating Parkinson′s disease.

Sonstige Hinweise

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

Kit-Komponenten auch einzeln erhältlich

Produkt-Nr.
Beschreibung
SDB
  • RABELADAELISA 1X Assay/Sample Diluent Buffer A (Item D1)SDB
  • RABELADBELISA 5X Assay/Sample Diluent Buffer B (Item E1)SDB
  • RABSTOP3ELISA Stop Solution (Item I)SDB
  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)SDB
  • RABWASH420X Wash Buffer (Item B)SDB

Piktogramme

Corrosion
GHS05

Signalwort

Warning

H-Sätze

H290

P-Sätze

P234 - P390

Gefahreneinstufungen

Met. Corr. 1

Lagerklassenschlüssel

8A - Combustible corrosive hazardous materials

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

Besitzen Sie dieses Produkt bereits?

In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Association analysis of the glial cell line-derived neurotrophic factor (GDNF) gene in schizophrenia
Williams HJ, et al.
Schizophrenia Research, 97(1-3), 271-276 (2007)
Liliana Brambilla et al.
Human molecular genetics, 25(14), 3080-3095 (2016-06-12)
Considerable evidence indicates that neurodegeneration in amyotrophic lateral sclerosis (ALS) can be conditioned by a deleterious interplay between motor neurons and astrocytes. Astrocytes are the major glial component in the central nervous system (CNS) and fulfill several activities that are
The reversible effects of glial cell line--derived neurotrophic factor (GDNF) in the human brain
Ayanlaja A, et al.
Seminars in Cancer Biology, 53(3), 212-222 (2018)
Distribution of GFRA1-expressing spermatogonia in adult mouse testis
Grasso M, et al.
Reproduction (Cambridge, England), 143(3) (2012)
Wenxing Zhao et al.
Neuroscience letters, 637, 108-113 (2016-11-27)
Inflammatory and neurotrophic factors are involved in postherpetic neuralgia (PHN), but the association of these factors in the cerebrospinal fluid (CSF) with the level of pain is poorly known. The present study aimed to examine the changes in neurotrophic and

Unser Team von Wissenschaftlern verfügt über Erfahrung in allen Forschungsbereichen einschließlich Life Science, Materialwissenschaften, chemischer Synthese, Chromatographie, Analytik und vielen mehr..

Setzen Sie sich mit dem technischen Dienst in Verbindung.