R4780

RACK1 human

recombinant, expressed in E. coli, >90% (SDS-PAGE), buffered aqueous solution

• Synonym(e): Receptor for activated protein kinase C
• UNSPSC-Code: 12352200
• NACRES: NA.32

Eigenschaften

• Rekombinant: expressed in E. coli
• Assay: >90% (SDS-PAGE)
• Form: buffered aqueous solution
• Mol-Gew.: 37 kDa
• UniProt-Hinterlegungsnummer: P63244
• Versandbedingung: dry ice
• Lagertemp.: −20°C
• Angaben zum Gen: human ... GNB2L1(10399)

Beschreibung

Biochem./physiol. Wirkung

RACK1 (receptor of activated protein kinase C1) is an intracellular adapter protein, which belongs to a class of intracellular receptor proteins that bind activated members of the protein kinase C family. RACK1 serves as a scaffold protein for a wide range of kinases and membrane-bound receptors. RACK1 is a member of the tryptophane-aspartate (WD) family known for its propeller-like structure. Literature strongly indicates that RACK1 plays an important role in intracellular signaling at several functional levels. RACK1, a substrate for several kinases, is involved in the regulation of Src function and cell growth.

RACK1 is an intracellular receptor protein that binds activated members of the protein kinase C family.

Physikalische Form

Supplied in a 0.2 μm filtered solution of 0.02 M Tris buffer, pH 8.0, with 0.15 M NaCl, 5 mM DTT, 0.1% CHAPS, and 30% glycerol (w/v).

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)