R101

Ranitidin -hydrochlorid

solid

• Empirische Formel (Hill-System): C₁₃H₂₂N₄O₃S · HCl
• CAS-Nummer: 66357-59-3
• Molekulargewicht: 350.86
• EG-Nummer: 266-333-0
• MDL-Nummer: MFCD00069339
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 24277803
• NACRES: NA.77

Eigenschaften

• Form: solid
• Farbe: tan
• Löslichkeit: H₂O: 1.8 mg/mL; 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 7.0 mg/mL
• Ersteller: GlaxoSmithKline
• SMILES String: Cl[H].CN\C(NCCSCc1ccc(CN(C)C)o1)=C\[N+]([O-])=O
• InChI: 1S/C13H22N4O3S.ClH/c1-14-13(9-17(18)19)15-6-7-21-10-12-5-4-11(20-12)8-16(2)3;/h4-5,9,14-15H,6-8,10H2,1-3H3;1H/b13-9-;
• InChIKey: GGWBHVILAJZWKJ-CHHCPSLASA-N
• Angaben zum Gen: human ... HRH2(3274)

Beschreibung

Anwendung

Ranitidine hydrochloride has been used as a reference compound for the development and validation of parallel artificial membrane permeability assay (PAMPA).

Biochem./physiol. Wirkung

Ranitidine is mainly used to treat gastrointestinal impairment instigated by non-steroidal anti-inflammatory drugs (NSAIDs).

H₂ Histamin-Rezeptorantagonist; Antiulcusmittel

Leistungsmerkmale und Vorteile

This compound is a featured product for ADME Tox research. Click here to discover more featured ADME Tox products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the Histamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Sicherheitshinweise

• Piktogramme: GHS08,GHS07
• Signalwort: Danger
• H-Sätze: H315,H317,H319,H334,H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 2
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)