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Merck

PLA0012

Sigma-Aldrich

Rabbit anti-Phospho SMC1 (S957) Antibody, Affinity Purified

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Synonym(e):

CDLS2, DXS423E, KIAA0178, SB1.8, SMC protein 1A, SMC-1-alpha, SMC-1A, SMC1, SMC1 (structural maintenance of chromosomes 1, SMC1 structural maintenance of chromosomes 1-like 1 (yeast), SMC1L1, SMC1alpha, Smcb, segregation of mitotic chromosomes 1, yeast)-like 1

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About This Item

UNSPSC-Code:
12352203
NACRES:
NA.41

Biologische Quelle

rabbit

Qualitätsniveau

Antikörperform

affinity purified immunoglobulin

Antikörper-Produkttyp

primary antibodies

Qualität

Powered by Bethyl Laboratories, Inc.

Speziesreaktivität

human

Methode(n)

immunoprecipitation (IP): 2- 6 μg/mg
western blot: 1:200-1:2,000

Hinterlegungsnummer

NP_006297.2

Versandbedingung

wet ice

Lagertemp.

2-8°C

Angaben zum Gen

human ... SMC1A(8243)

Immunogen

Immunogen for PLA0012 was a phosphorylated synthetic peptide, which represented a portion of human Structural Maintenance of Chromosomes 1 (GeneID 8243) around serine 957 according to the numbering given in entry NP_006297.2.

Physikalische Form

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% sodium azide

Sonstige Hinweise

Structural maintenance of chromosomes (SMC) proteins are part of the cohesin and condensin multisubunit complexes that play a critical role in chromosome organization, segregation, gene regulation, and DNA repair. The core cohesin complex includes a heterodimer of SMC1 and SMC3 that functions by forming a ring-like structure that holds sister chromatids together. Cohesin is important to sister chromatid separation and segregation during mitosis and meiosis and also plays a role in double-strand break repair by homologous recombination.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

12 - Non Combustible Liquids

WGK

nwg

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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