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O5501

Sigma-Aldrich

Oxyphenonium bromide

Synonym(e):

2-([Cyclohexylhydroxyphenylacetyl]oxy)-N,N-diethyl-N-methylethanaminium bromide

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About This Item

Lineare Formel:
C21H34NO3Br
CAS-Nummer:
50-10-2
Molekulargewicht:
428.40
EG-Nummer:
200-010-7
MDL-Nummer:
MFCD00050259
UNSPSC-Code:
12161900
PubChem Substanz-ID:
24898019

Beschreibung

cationic

Assay

>98% (TLC)

Mol-Gew.

428.40 g/mol

SMILES String

Br.CC[N](C)(CC)CCOC(=O)C(O)(C1CCCCC1)c2ccccc2

InChI

1S/C21H34NO3.BrH/c1-4-22(3,5-2)16-17-25-20(23)21(24,18-12-8-6-9-13-18)19-14-10-7-11-15-19;/h6,8-9,12-13,19,24H,4-5,7,10-11,14-17H2,1-3H3;1H

InChIKey

JKJFWDDPBNHJPV-UHFFFAOYSA-N

Anwendung

Oxyphenonium bromide has been used in a study to assess masking mechanisms of bitter taste of drugs. It has also been used in a study to investigate stoichiometric and microenvironmental effects on hydrolysis of propantheline in cyclodextrin solutions.

Piktogramme

Exclamation mark
GHS07

Signalwort

Warning

Gefahreneinstufungen

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

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Analysenzertifikate (COA)

Lot/Batch Number
044F0691

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Marian Turcani et al.
Scientific reports, 9(1), 2586-2586 (2019-02-24)
Successful adaptation to passive hyperthermia requires continual adjustment of circulation, which is mediated mainly by the autonomic nervous system. The goal of this study was to explore the alterations in spontaneous cardiovagal baroreflex sensitivity (BRS) during exposure to a hot
Alaa El-Gindy et al.
Journal of AOAC International, 90(5), 1250-1257 (2007-10-25)
A high-performance liquid chromatographic (HPLC) method was developed for determination of oxyphenonium bromide (OX) and its degradation product. The method was based on the HPLC separation of OX from its degradation product, using a cyanopropyl column at ambient temperature with
Noriaki Funasaki et al.
Chemical & pharmaceutical bulletin, 54(8), 1155-1161 (2006-08-02)
The masking mechanisms of the bitter taste of propantheline bromide (PB) and oxyphenonium (OB) bromide by native and modified cyclodextrins, saccharides, surfactants, organic acids, nonionic and anionic polymers, and other compounds were investigated with ion selective electrodes. The intensity of
Galina I Nezhinskaya et al.
Life sciences, 80(24-25), 2342-2346 (2007-05-15)
Cholinergic drugs can modulate anaphylactic shock and change lymphocyte functions. Plasma proteins modulate effects of muscarinic antagonists during anaphylactic shock. The present investigation was carried out to study the antianaphylactic activity of methacine (antagonist at muscarinic receptors) in combination with
[Use of endoscopic drug block of the vagus nerve and cryotherapy in the treatment of peptic ulcer].
V A Grushko et al.
Klinichna khirurhiia, (8)(8), 12-13 (1996-01-01)
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