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M3656

Sigma-Aldrich

Mephentermin -hemisulfat (Salz)

Synonym(e):

N,α,α-Trimethylphenethylamin -hemisulfat (Salz)

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About This Item

Lineare Formel:
C11H17N · 1/2H2SO4
CAS-Nummer:
1212-72-2
Molekulargewicht:
212.30
EG-Nummer:
214-923-3
MDL-Nummer:
MFCD00083413
UNSPSC-Code:
12352200
PubChem Substanz-ID:
24896864

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

Anwendung(en)

forensics and toxicology
veterinary

SMILES String

OS(O)(=O)=O.CNC(C)(C)Cc1ccccc1.CNC(C)(C)Cc2ccccc2

Biochem./physiol. Wirkung

α-Adrenoceptor-Agonist.

Piktogramme

Skull and crossbones
GHS06

Signalwort

Danger

H-Sätze

H301

P-Sätze

P301 + P310

Gefahreneinstufungen

Acute Tox. 3 Oral

Lagerklassenschlüssel

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Analysenzertifikate (COA)

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B Bhattarai et al.
JNMA; journal of the Nepal Medical Association, 49(177), 23-28 (2010-12-25)
Hypotension is common following spinal anesthesia. Various vasopressors have been indicated to prevent it. The study compares three such agents namely phenylephrine, ephedrine and mephentermine. The study included 90 patients undergoing elective and emergency cesarean section who developed hypotension following
T Murali Krishna et al.
European journal of anaesthesiology, 25(4), 299-306 (2007-09-26)
Intrathecal ketamine produces a short period of analgesia with stable haemodynamics. Midazolam with bupivacaine prolongs the duration of analgesia when administered intrathecally but does not prevent hypotension. The objective of this study was to assess the effect of a combination
Up-down study--is the analysis adequate?
J K Makkar et al.
Anaesthesia and intensive care, 38(1), 208-209 (2010-03-03)
M Mohta et al.
Anaesthesia and intensive care, 37(4), 568-570 (2009-08-18)
This study was designed to determine the minimum effective dose (ED50) of mephentermine for prevention of post-spinal hypotension in women undergoing elective caesarean section. Dixon's up-down method of sequential allocation was used to determine the patient's dose of vasopressor drug.
M Mori et al.
Xenobiotica; the fate of foreign compounds in biological systems, 19(3), 287-299 (1989-03-01)
1. Excretion of urinary and biliary radioactivity, and metabolites of [3H]mephentermine (MP), after i.p. or subcutaneous administration of [3H]MP to male Wistar rats, were determined by preparative t.l.c.-liquid scintillation counting. 2. About 45% of the radioactivity administered i.p. was excreted
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