M3316

Myoseverin B

≥97% (HPLC)

• Synonym(e): 2,6-Bis(4-methoxybenzylamino)-9-cyclohexylpurine
• Empirische Formel (Hill-System): C₂₇H₃₂N₆O₂
• CAS-Nummer: 361431-27-8
• Molekulargewicht: 472.58
• MDL-Nummer: MFCD08276922
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 24724538
• NACRES: NA.77

Eigenschaften

• Assay: ≥97% (HPLC)
• Löslichkeit: DMSO: soluble; H₂O: insoluble
• Versandbedingung: dry ice
• Lagertemp.: −20°C
• SMILES String: COc1ccc(CNc2nc(NCc3ccc(OC)cc3)c4ncn(C5CCCCC5)c4n2)cc1
• InChI: 1S/C27H32N6O2/c1-34-22-12-8-19(9-13-22)16-28-25-24-26(33(18-30-24)21-6-4-3-5-7-21)32-27(31-25)29-17-20-10-14-23(35-2)15-11-20/h8-15,18,21H,3-7,16-17H2,1-2H3,(H2,28,29,31,32)
• InChIKey: ZUZXYJOSNSTJMU-UHFFFAOYSA-N

Beschreibung

Biochem./physiol. Wirkung

Myoseverin, a new microtubule-binding molecule, acts reversibly on myoblast proliferation without the cytotoxic effects displayed by nonpurine-based microtubule-disrupting molecules, like taxol, vinblastine, nocodazole. Myoseverin can be effectively used for the inhibition of new vessel growth by inhibiting endothelial cell function and differentiation of progenitor cells.

Tubulin polymerization inhibitor.

Sicherheitshinweise

• Lagerklassenschlüssel: 13 - Non Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)