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L9750

Sigma-Aldrich

Leu-Gly-Gly

Synonym(e):

L-Leucyl-glycyl-glycin

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About This Item

Lineare Formel:
(CH3)2CHCH2CH(NH2)CONHCH2CONHCH2COOH
CAS-Nummer:
1187-50-4
Molekulargewicht:
245.28
Beilstein:
1728928
EG-Nummer:
214-698-1
MDL-Nummer:
MFCD00065942
UNSPSC-Code:
12352209
PubChem Substanz-ID:
24896460
NACRES:
NA.26

Assay

≥98% (TLC)

Form

powder

Methode(n)

ligand binding assay: suitable

Farbe

white to off-white

Lagertemp.

−20°C

SMILES String

CC(C)C[C@H](N)C(=O)NCC(=O)NCC(O)=O

InChI

1S/C10H19N3O4/c1-6(2)3-7(11)10(17)13-4-8(14)12-5-9(15)16/h6-7H,3-5,11H2,1-2H3,(H,12,14)(H,13,17)(H,15,16)/t7-/m0/s1

InChIKey

VWHGTYCRDRBSFI-ZETCQYMHSA-N

Angaben zum Gen

human ... SLC15A1(6564)

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Amino Acid Sequence

Leu-Gly-Gly

Biochem./physiol. Wirkung

Leucylglycylglycine (DL-Leu-Gly-Gly) may be used to study the effects of branched-chain di- and tripeptides on cell envelope-associated proteinases (CEPs) activity. L-Leu-Gly-Gly may be used as a substrate to study the kinetics of tripeptide aminopeptidase (EC 3.4.11.4) and other peptidase(s) such as leucylglycylglycine aminopeptidase (EC 3.4.1.3).

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)

Analysenzertifikate (COA)

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S Kanda et al.
Clinical chemistry, 30(6), 843-846 (1984-06-01)
This is a method for measuring tripeptide aminopeptidase (EC 3.4.11.4) activity in serum. L- Leucylglycylglycine is used as substrate, and the reaction is followed by monitoring the absorbance increase at 340 nm when NAD+ is reduced to NADH in the
María B Espeche Turbay et al.
Journal of agricultural and food chemistry, 57(18), 8607-8611 (2009-09-17)
The cell-envelope-associated proteinase of Lactobacillus delbrueckii subsp. lactis CRL 581 (PrtL) has an essential role in bacterial growth and contributes to the development of the organoleptic properties of hard cheeses and to the release of bioactive health-beneficial peptides from milk
L C Masek et al.
Experimental hematology, 22(12), 1203-1209 (1994-11-01)
"Homing" of hematopoietic progenitor cells to the bone marrow occurs during the clinical practice of bone marrow transplantation. Its mechanism is unknown, although adhesive interactions between hematopoietic cells and sinusoidal endothelium in the bone marrow may be implicated. Studies of
T Agatsuma et al.
Parasitology, 91 ( Pt 3), 489-497 (1985-12-01)
An enzyme analysis of diploid and triploid Paragonimus westermani was conducted using starch gel electrophoresis. In total, 16 enzymes, probably encoded by 18 loci, were studied for 3 populations of the diploid form sampled from 2 localities, and 4 populations
Elvira María Hebert et al.
Applied and environmental microbiology, 74(12), 3682-3689 (2008-04-22)
The cell envelope-associated proteinases (CEPs) of the lactobacilli have key roles in bacterial nutrition and contribute to the development of the organoleptic properties of fermented milk products as well, as they can release bioactive health-beneficial peptides from milk proteins. The
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