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K4769

Sigma-Aldrich

Kojibiose

≥98% (HPLC)

Synonym(e):

α-D-Glc-(1→2)-D-Glc, 2-O-α-D-Glucopyranosyl-D-glucose

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About This Item

Empirische Formel (Hill-System):
C12H22O11
CAS-Nummer:
2140-29-6
Molekulargewicht:
342.30
MDL-Nummer:
MFCD00214308
UNSPSC-Code:
12352201
PubChem Substanz-ID:
329817148
NACRES:
NA.25

Assay

≥98% (HPLC)

Form

powder

Methode(n)

HPLC: suitable

Farbe

white to off-white

Löslichkeit

water: 5 mg/mL, clear, colorless

Lagertemp.

−20°C

SMILES String

OCC(O)C(O)C(O)C(OC1OC(CO)C(O)C(O)C1O)C=O

InChI

1S/C12H22O11/c13-1-4(16)7(17)8(18)5(2-14)22-12-11(21)10(20)9(19)6(3-15)23-12/h2,4-13,15-21H,1,3H2

InChIKey

PZDOWFGHCNHPQD-UHFFFAOYSA-N

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Anwendung

Kojibiose, a disaccharide product of glucose caramelization and an inhibitor of plant glucosidase I, may be used to help identify and characterize glucosidase I enzymes involved in terminal deglycosylation of high-mannose oligosaccharides. Kojibiose may be used as a substrate to study the biological species, enzymes and catabolic processes that catabolize it as an energy source. Kojibiose may be used to identify, differentiate and characterize kojibiose phosphorylase(s) (KP).

Biochem./physiol. Wirkung

Kojibiose is an inhibitor of plant glucosidase I. It inhibits the removal of terminal glucose from the high-mannose oligosaccharide (Glc)3(Man)9(GlcNAc)2, either from the free oligosaccharide or from the oligosaccharide attached to a protein via N-linkage.

Sonstige Hinweise

To gain a comprehensive understanding of our extensive range of Disaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Glucose-tetrasaccharid ≥99.0% (TLC)

Sigma-Aldrich

78544

Glucose-tetrasaccharid

Nystose analytical standard

Supelco

56218

Nystose

Isomaltose analytical standard

Supelco

05389

Isomaltose

Satoshi Okada et al.
The FEBS journal, 281(3), 778-786 (2013-11-22)
Glycoside hydrolase (GH) family 65 contains phosphorylases acting on maltose (Glc-α1,4-Glc), kojibiose (Glc-α1,2-Glc), trehalose (Glc-α1,α1,-Glc), and nigerose (Glc-α1,3-Glc). These phosphorylases can efficiently catalyze the reverse reactions with high specificities, and thus can be applied to the practical synthesis of α-glucosyl
Jong-Hyun Jung et al.
Journal of bacteriology, 196(5), 1122-1131 (2014-01-07)
A unique gene cluster responsible for kojibiose utilization was identified in the genome of Pyrococcus sp. strain ST04. The proteins it encodes hydrolyze kojibiose, a disaccharide product of glucose caramelization, and form glucose-6-phosphate (G6P) in two steps. Heterologous expression of
Jarred Yasuhara-Bell et al.
Microorganisms, 8(3) (2020-03-11)
Rathayibacter toxicus is a Gram-positive, nematode-vectored bacterium that infects several grass species in the family Poaceae. Unique in its genus, R. toxicus has the smallest genome, possesses a complete CRISPR-Cas system, a vancomycin-resistance cassette, produces tunicamycin, a corynetoxin responsible for
Ana Vila Verde et al.
The journal of physical chemistry. B, 115(21), 7069-7084 (2011-05-13)
Molecular level insight into water structure and structural dynamics near proteins, lipids, and nucleic acids is critical to the quantitative understanding of many biophysical processes. Unfortunately, understanding hydration and hydration dynamics around such large molecules is challenging because of the
S Ogawa et al.
Carbohydrate research, 307(1-2), 83-95 (1998-07-11)
Two kojibiose-type pseudo-disaccharides and a trisaccharide, containing a 5-amino-1,2,3,4-cyclopentanetetrol derivative or valienamine, linked by way of nitrogen bridges to the sugar residues, have been designed and synthesized as processing alpha-glucosidase I inhibitors. Synthesis of the pseudo-disaccharides was carried out starting
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