GW22823

Anti-BAT3 antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: chicken
• Konjugat: unconjugated
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous solution
• Speziesreaktivität: human, rat
• Hersteller/Markenname: Genway 15-288-22823
• Methode(n): western blot: suitable
• NCBI-Hinterlegungsnummer: NP_542434.1
• UniProt-Hinterlegungsnummer: P46379
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... BAT3(7917)

Beschreibung

Allgemeine Beschreibung

BAT3 is a gene from major histocompatibility complex. In humans, it is localized in the class III region of the human major histocompatibility complex on chromosome 6. It consists of an ubiquitin homology region at the N-terminal end, short tracts of polyproline and polyglycine, a zinc finger-like domain and a nuclear localization signal (NLS) at the C- terminus end. It is a member of BAG family of proteins. The major responsibility of BAG proteins is to negatively control the chaperone function of the Hsp70 family.

Immunogen

Immunogen Sequence: GI # 18375632, sequence 2-250

Recombinant HLA-B associated transcript-3 isoform b

Anwendung

Anti-BAT3 antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

Biochem./physiol. Wirkung

Large proline-rich protein BAT3 is a protein encoded by the BAT3 gene in humans. It is very rich in proline and includes short tracts of polyproline, polyglycine and charged amino acids. BAT3 is similar to other proteins with large proline-rich domains, such as some nuclear proteins, collagens, elastin and synapsin. It has distinct functions in the cytosol and in the nucleus. It is also associated with controlling of apoptosis and regulating heat shock protein (HSP) 70 activity.

Physikalische Form

Solution in phosphate buffered saline containing 0.02% sodium azide.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)