GE17-1279-02

rProtein A Sepharose^™ Fast Flow

Cytiva 17-1279-02, pack of 25 mL

• UNSPSC-Code: 41106500
• NACRES: NA.56

Eigenschaften

• ligand: recombinant protein A (E. coli)
• Verpackung: pack of 25 mL
• Hersteller/Markenname: Cytiva 17-1279-02
• Lagerbedingungen: (20% Ehtanol)
• Matrix: 4% cross-linked agarose
• Partikelgröße: 60-165 μm
• Durchschnittlicher Durchmesser: 90 μm (d50v)
• cleaning in place: 2-11
• working range: 3-10
• Kapazität: ~50 mg binding capacity (human lgG/ml medium)
• Eignung: suitable for bioprocess medium
• Lagertemp.: 2-8°C

Beschreibung

Allgemeine Beschreibung

rProtein A Sepharose 4 Fast Flow is an affinity resin for antibody purification at laboratory and process scale.

Monoclonal and polyclonal antibody purification

rProtein A Sepharose 4 Fast Flow is built upon the well-established Sepharose Fast Flow platform and is used in many approved monoclonal antibody processes. It is composed of recombinant protein A coupled to the cross-linked 4% agarose base matrix.The highly crosslinked agarose resin enables high flow rates and high productivity.

Protein A resin characteristics

The recombinant protein is produced in E. coli and engineered with an oriented coupling to enhance binding capacity. Epoxy-based coupling ensures low ligand leakage. Specificity of the recombinant protein for the Fc region of IgG is similar to the native protein, giving a high degree of selectivity and yield.

Streamlined scale up

Scale-up with this resin is straightforward and is further aided by a range of prepacked process development tools, making purification scale-up straightforward.

Leistungsmerkmale und Vorteile

• For monoclonal and polyclonal antibody purification at both laboratory and process scale.
• Well established among Protein A resins as excellent for monoclonal antibody (mAb) processes.
• Free from animal-derived components.
• Hydrophilic base matrix ensures low levels of non-specific binding and low levels of host cell-derived impurities in the elution pool.
• Fulfills industrial demands for security of supply, robust performance, and regulatory support.

Lagerung und Haltbarkeit

Please be aware this product may be shipped 90 days before the expiration date. For more information on the batch specific expiration date, please contact technical service.

Hinweis zur Analyse

To view the Certificate of Analysis for this product, please visit www.cytiva.com.

Rechtliche Hinweise

Sepharose is a trademark of Cytiva

Sicherheitshinweise

• Piktogramme: GHS02
• Signalwort: Warning
• H-Sätze: H226
• P-Sätze: P280 - P210 - P241 - P235 - P303 + P361 + P353 - P501
• Lagerklassenschlüssel: 3 - Flammable liquids