F1305

Anti-FEN-1 (C-terminal) antibody produced in rabbit

~1 mg/mL, affinity isolated antibody, buffered aqueous solution

• Synonym(e): Anti-Flap endonuclease, Anti-Flap structure-specific endonuclease 1
• MDL-Nummer: MFCD09039190
• UNSPSC-Code: 12352203

Eigenschaften

• Biologische Quelle: rabbit
• Konjugat: unconjugated
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous solution
• Mol-Gew.: antigen 45 kDa
• Speziesreaktivität: human
• Konzentration: ~1 mg/mL
• Methode(n): immunoprecipitation (IP): 2-4 μg using HEK 293T cell lysates; indirect immunofluorescence: 5-10 μg/mL using paraformaldehyde-fixed HEK 293T cells; western blot: 0.5-1 μg/mL using K562 cell lysates
• UniProt-Hinterlegungsnummer: P39748
• Versandbedingung: dry ice
• Lagertemp.: −20°C
• Angaben zum Gen: human ... FEN1(2237) ; mouse ... Fen1(14156) ; rat ... Fen1(84490)

Beschreibung

Immunogen

synthetic peptide corresponding to amino acids 367-380 of human FEN-1, conjugated to KLH via an N-terminal added cysteine residue. The corresponding sequence in rat and mouse differs by one and two amino acids, respectively.

Zielbeschreibung

FEN-1 (C-terminal) encodes a protein that removes 5′ overhanging flaps in DNA repair and processes the 5′ ends of Okazaki fragments in lagging strand DNA synthesis. Direct physical interaction between this protein and AP endonuclease 1 during long-patch b

Physikalische Form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 12 - Non Combustible Liquids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)