E6510

Ergosterol

≥75%

• Synonym(e): 3β-Hydroxy-5,7,22-ergostatrien, 5,7,22-Ergostatrien-3β-ol, Provitamin D₂
• Empirische Formel (Hill-System): C₂₈H₄₄O
• CAS-Nummer: 57-87-4
• Molekulargewicht: 396.65
• Beilstein: 2338604
• EG-Nummer: 200-352-7
• MDL-Nummer: MFCD00003623
• UNSPSC-Code: 12352205
• PubChem Substanz-ID: 24894628
• NACRES: NA.77

Eigenschaften

• Biologische Quelle: microbial
• Assay: ≥75%
• Form: powder
• Farbe: white to off-white
• mp (Schmelzpunkt): 156-158 °C (lit.)
• Lagertemp.: 2-8°C
• SMILES String: [H][C@@]1(CC[C@@]2([H])C3=CC=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)\C=C\[C@H](C)C(C)C
• InChI: 1S/C28H44O/c1-18(2)19(3)7-8-20(4)24-11-12-25-23-10-9-21-17-22(29)13-15-27(21,5)26(23)14-16-28(24,25)6/h7-10,18-20,22,24-26,29H,11-17H2,1-6H3/b8-7+/t19-,20+,22-,24+,25-,26-,27-,28+/m0/s1
• InChIKey: DNVPQKQSNYMLRS-APGDWVJJSA-N

Beschreibung

Allgemeine Beschreibung

Ergosterol or provitamin D2 is a biological precursor of Vitamin D2. It is found predominantly in cell membranes of fungi and protists such as trypanosomes.

Anwendung

Ergosterol has been used:

• as a component of yeast cell monolayer models, to study the effects of steroidal and triterpenoid saponins on the monolayers
• as a standard sample, to isolate and identify a fungal metabolite fraction containing ergosterol
• as a component of the culture medium to isolate the CYP51^RNAi phenotype of Trypanosoma brucei gambiense, to verify ergosterol biosynthesis

Biochem./physiol. Wirkung

Ergosterol has a role in maintaining the integrity of the cell membrane and its fluidity. The sterol has anti-tumor and anti-inflammatory properties.

Sicherheitshinweise

• H-Sätze: H413
• P-Sätze: P273
• Gefahreneinstufungen: Aquatic Chronic 4
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Persönliche Schutzausrüstung: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges