E4404

Anti-EphA8 antibody produced in goat

affinity isolated antibody, lyophilized powder

• MDL-Nummer: MFCD04040318
• UNSPSC-Code: 51111800
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: goat
• Qualitätsniveau: 100
• Konjugat: unconjugated
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: lyophilized powder
• Speziesreaktivität: mouse
• Methode(n): indirect ELISA: 0.5-1.0 μg/mL; western blot: 0.1-0.2 μg/mL
• UniProt-Hinterlegungsnummer: O09127
• Lagertemp.: −20°C
• Angaben zum Gen: mouse ... Epha8(13842)

Beschreibung

Allgemeine Beschreibung

The antibody demonstrates ~5% cross-reactivity with recombinant mouse EphA6, EphA7, EphA2, and EphA3 in ELISA and immunoblotting assays. Also, there is approximately 5% cross-reactivity with recombinant human EphA1 and recombinant rat EphA5.

Immunogen

purified recombinant mouse EphA8 extracellular domain.

Biochem./physiol. Wirkung

EPH receptor A8 is a protein-tyrosine kinase family that belongs to the ephrin receptor subfamily. It regulates developmental events, particularly those of the nervous system. EphA8 binds p110γ isoform of PI3-kinase and regulates the integrin-mediated cell adhesion.

Physikalische Form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)