D4001

2′-Deoxyuridine 5′-triphosphate sodium salt

≥95%

• Synonym(e): dUTP sodium salt
• Empirische Formel (Hill-System): C₉H₁₅N₂O₁₄P₃ · xNa⁺
• CAS-Nummer: 102814-08-4
• Molekulargewicht: 468.14 (free acid basis)
• MDL-Nummer: MFCD00084701
• UNSPSC-Code: 41106305
• PubChem Substanz-ID: 24893804
• NACRES: NA.51

Eigenschaften

• Biologische Quelle: synthetic (organic)
• Assay: ≥95%
• Form: powder
• Lagertemp.: −20°C
• SMILES String: [Na].OC1CC(OC1COP(O)(=O)OP(O)(=O)OP(O)(O)=O)N2C=CC(=O)NC2=O
• InChI: 1S/C9H15N2O14P3.Na.H/c12-5-3-8(11-2-1-7(13)10-9(11)14)23-6(5)4-22-27(18,19)25-28(20,21)24-26(15,16)17;;/h1-2,5-6,8,12H,3-4H2,(H,18,19)(H,20,21)(H,10,13,14)(H2,15,16,17);;
• InChIKey: FVFWWPFKJNTHIQ-UHFFFAOYSA-N

Beschreibung

Anwendung

2′-Deoxyuridine 5′-triphosphate (dUTP) may be used to study the distribution, specificity and kinetics of deoxyuridine 5′-triphosphate nucleotidohydrolase(s) (dUTPase, EC 3.6.1.23). dUTPase are important enzymes that protect cells from the incorporation of dUTP into DNA.dUTP is a component of the TUNEL (terminal deoxyribonucleotidyl-transferase-(TdT)-mediated deoxyuridine-5′-triphosphate- (dUTP) nick-end labeling) test. TUNEL is a common method for detecting DNA fragmentation that results from apoptotic signaling cascades.

2′-Deoxyuridine 5′-triphosphate sodium salt has been used in the extraction of white muscles from the African catfish.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable