C9377

Chenodesoxycholsäure

• Synonym(e): 3α,7α-Dihydroxy-5β-cholansäure, 5β-Cholansäure-3α,7α-diol, Chenodiol
• Empirische Formel (Hill-System): C₂₄H₄₀O₄
• CAS-Nummer: 474-25-9
• Molekulargewicht: 392.57
• Beilstein: 3219887
• EG-Nummer: 207-481-8
• MDL-Nummer: MFCD00064142
• UNSPSC-Code: 12352106
• PubChem Substanz-ID: 24893153
• NACRES: NA.25

Eigenschaften

• Beschreibung: anionic
• Form: powder
• Mol-Gew.: 392.57 g/mol
• Methode(n): protein quantification: suitable
• CMC: (3); 3
• mp (Schmelzpunkt): 165-167 °C (lit.)
• Funktionelle Gruppe: carboxylic acid
• Versandbedingung: ambient
• Lagertemp.: room temp
• SMILES String: C[C@H](CCC(O)=O)[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C
• InChI: 1S/C24H40O4/c1-14(4-7-21(27)28)17-5-6-18-22-19(9-11-24(17,18)3)23(2)10-8-16(25)12-15(23)13-20(22)26/h14-20,22,25-26H,4-13H2,1-3H3,(H,27,28)/t14-,15+,16-,17-,18+,19+,20-,22+,23+,24-/m1/s1
• InChIKey: RUDATBOHQWOJDD-BSWAIDMHSA-N
• Angaben zum Gen: human ... CYP1A2(1544) , NR1H4(9971)

Beschreibung

Allgemeine Beschreibung

Chenodeoxycholic acid is a bile acid synthesized in the liver from cholesterol.

Anwendung

Chenodeoxycholic acid has been used in a study to assess its effects as a long-term replacement therapy for cerebrotendinous xanthomatosis (CTX). It has also been used in a study to investigate its effects on the small-intestinal absorption of bile acids in patients with ileostomies.

Biochem./physiol. Wirkung

Bile Acid

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315,H319
• P-Sätze: P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 2
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)