C0610

8-Chloroadenosine-3′,5′-cyclic monophosphorothioate, Rp-isomer

≥99% (HPLC)

• Synonym(e): Rp-8-Cl-cAMPS
• Empirische Formel (Hill-System): C₁₀H₁₀ClN₅O₅PSNa
• CAS-Nummer: 142754-27-6
• Molekulargewicht: 401.70
• UNSPSC-Code: 41106305
• PubChem Substanz-ID: 329774805
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 200
• Assay: ≥99% (HPLC)
• Form: solid
• Verpackung: vial of 5 μmol
• Lagertemp.: −20°C
• SMILES String: Nc1ncnc2n([C@@H]3O[C@@H]4CO[P@@](S)(=O)O[C@H]4[C@H]3O)c(Cl)nc12
• InChI: 1S/C10H11ClN5O5PS/c11-10-15-4-7(12)13-2-14-8(4)16(10)9-5(17)6-3(20-9)1-19-22(18,23)21-6/h2-3,5-6,9,17H,1H2,(H,18,23)(H2,12,13,14)/t3-,5-,6-,9-,22-/m1/s1
• InChIKey: PJAHPRNGOHUYQD-KVBUDSETSA-N

Beschreibung

Biochem./physiol. Wirkung

Competitive inhibitor of cyclic AMP-dependent protein kinase A (PKA) type I. Membrane-permeable analog of the cAMP inhibitor Rp-cAMPS (Prod. No. A-165).

Leistungsmerkmale und Vorteile

This compound is featured on the PKA & PKG page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)