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Merck

B9265

Sigma-Aldrich

Anti-Mouse IgM (μ-chain specific)–Biotin antibody produced in goat

affinity isolated antibody, buffered aqueous solution

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About This Item

MDL-Nummer:
UNSPSC-Code:
12352203
NACRES:
NA.46

Biologische Quelle

goat

Konjugat

biotin conjugate

Antikörperform

affinity isolated antibody

Antikörper-Produkttyp

secondary antibodies

Klon

polyclonal

Form

buffered aqueous solution

Methode(n)

direct ELISA: 1:20,000

Lagertemp.

2-8°C

Posttranslationale Modifikation Target

unmodified

Allgemeine Beschreibung

IgM is a glycoprotein antibody that regulates humoral immune responses. Mouse IgM is involved in modulating B cell memory . This antibody isotype has also been implicated in the development of autoimmune responses associated with the pathogenesis of type 1 diabetes in mice . Anti-Mouse IgM (μ-chain specific)-Biotin antibody is specific for mouse IgM when tested against mouse IgA, IgG, and IgM by ELISA.

Immunogen

Mouse IgM

Anwendung

Anti-Mouse IgM (μ-chain specific)-Biotin antibody is suitable for use in immunocytochemistry (at 1:500 dilutions in methanol-fixed, sheep embryo sections) and direct ELISA (1:20,000).

Physikalische Form

Solution in 0.01 M phosphate buffered saline pH 7.4, containing 1% bovine serum albumin and 15 mM sodium azide

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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M Dattena et al.
Molecular reproduction and development, 73(1), 31-39 (2005-10-06)
This study was conducted to isolate, to culture, and to characterize embryonic cell lines from in vitro produced vitrified sheep blastocysts. Embryos were produced and vitrified at the expanded blastocyst stage. Ten inner cell masses arising from day 6-7 blastocysts
Christian Reichel et al.
Drug testing and analysis, 11(11-12), 1675-1697 (2019-11-24)
Follistatin, a myostatin-inhibiting protein, is prohibited according to chapter S4 of the "WADA 2019 List of Prohibited Substances and Methods". While currently no approved pharmaceutical formulations of follistatin are available, follistatin can be bought on the black market. Most of
J Côrte-Real et al.
Diabetologia, 55(6), 1761-1772 (2012-03-03)
We sought to determine whether the presence of natural autoreactive antibodies of B1a cell origin would play a role in the initiation of type 1 diabetes. We compared IgM repertoires and B1a cell compartments in NOD and C57BL/6 mice. Serum
Claude-Agnès Reynaud et al.
Cellular and molecular life sciences : CMLS, 69(10), 1625-1634 (2012-04-07)
Humoral memory is maintained by two types of persistent cells, memory B cells and plasma cells, which have different phenotypes and functions. Long-lived plasma cells can survive for a lifespan within a complex niche in the bone marrow and provide
Julie A Douthwaite et al.
mAbs, 7(1), 152-166 (2014-12-09)
Therapeutic monoclonal antibodies targeting G-protein-coupled receptors (GPCRs) are desirable for intervention in a wide range of disease processes. The discovery of such antibodies is challenging due to a lack of stability of many GPCRs as purified proteins. We describe here

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