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Dokumente

A9755

Sigma-Aldrich

cis-Androsteron

≥99%

Synonym(e):

3α-Hydroxy-5α-androstan-17-on, 5α-Androstan-3α-ol-17-on

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About This Item

Empirische Formel (Hill-System):
C19H30O2
CAS-Nummer:
53-41-8
Molekulargewicht:
290.44
Beilstein:
2217626
MDL-Nummer:
MFCD00003618
UNSPSC-Code:
51111800

Assay

≥99%

Arzneimittelkontrolle

regulated under CDSA - not available from Sigma-Aldrich Canada

mp (Schmelzpunkt)

181-184 °C (lit.)

SMILES String

[H][C@@]12CC[C@@]3([H])[C@]4([H])CCC(=O)[C@@]4(C)CC[C@]3([H])[C@@]1(C)CC[C@@H](O)C2

InChI

1S/C19H30O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h12-16,20H,3-11H2,1-2H3/t12-,13+,14-,15-,16-,18-,19-/m0/s1

InChIKey

QGXBDMJGAMFCBF-HLUDHZFRSA-N

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Biochem./physiol. Wirkung

Anabolic steroid

Piktogramme

Health hazard
GHS08

Signalwort

Danger

H-Sätze

H351,H360FD

Gefahreneinstufungen

Carc. 2 - Repr. 1B

Lagerklassenschlüssel

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Analysenzertifikate (COA)

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S H Doss et al.
Archives of pharmacal research, 22(5), 496-501 (1999-11-05)
The reaction of epi-androsterone with cyanoacetyl hydrazine (2) gave the hydrazone derivative 3. The reactivity of 3 towards chemical reagents was studied to give pyridine, thiazole and thiophene derivatives.
X Chai et al.
The Journal of biological chemistry, 272(52), 33125-33131 (1998-01-31)
We report a mouse cDNA that encodes a 317-amino acid short-chain dehydrogenase which recognizes as substrates 9-cis-retinol, 11-cis-retinol, 5alpha-androstan-3alpha,17beta-diol, and 5alpha-androstan-3alpha-ol-17-one. This cis-retinol/androgen dehydrogenase (CRAD) shares closest amino acid similarity with mouse retinol dehydrogenase isozymes types 1 and 2 (86
J Su et al.
Endocrinology, 140(11), 5275-5284 (1999-10-28)
17Beta-hydroxysteroid dehydrogenases (17betaHSDs) convert androgens and estrogens between their active and inactive forms, whereas retinol dehydrogenases catalyze the conversion between retinol and retinal. Retinol dehydrogenases function in the visual cycle, in the generation of the hormone retinoic acid, and some
Frank González et al.
Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, 19(1), 66-72 (2012-02-14)
Women with polycystic ovary syndrome (PCOS) have coagulation disturbances and inflammation, which increases the risk of atherothrombosis. We evaluated the status of circulating tissue factor (TF), the receptor for coagulation factor VII involved in atherothrombosis, in women with PCOS and
Ines Fürtbauer et al.
American journal of physical anthropology, 151(2), 311-315 (2013-04-17)
An extensive body of research exists on androgen secretion in males. Although androgens are also known to drive patterns of female reproductive physiology and behavior, little attention has been paid to these "male" hormones in females. Here, we examined female
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