A5384
Aconitase from porcine heart
Synonym(e):
Aconitate hydratase, Citrate (isocitrate) hydrolyase
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About This Item
Empfohlene Produkte
Biologische Quelle
Porcine heart
Form
solid
Mol-Gew.
~66 kDa by gel filtration
Lagertemp.
−20°C
Anwendung
Aconitase may be usefull in diabetes research as well as to study structural conservation between iron-responsive element binding proteins (IRE-BP) and isomerases .
Biochem./physiol. Wirkung
Aconitase catalyses the stereo-specific isomerization of citrate to isocitrate via cis-aconitate in the tricarboxylic acid cycle. Aconitase is inhibited by cyanide, sulfide and copper and mercury at low concentrations. It is competitively inhibited by trans-aconitate. Aconitase contains an internal Fe-S cluster which is responsible for its activity.
Einheitendefinition
One unit will convert 1.0 μmole of citrate (via cis-aconitate) to isocitrate per min at pH 7.4 at 25 °C.
Hinweis zur Analyse
Crude preparation containing aconitase activity
Lagerklassenschlüssel
11 - Combustible Solids
WGK
WGK 3
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
Persönliche Schutzausrüstung
Eyeshields, Gloves, type N95 (US)
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