A4470

Monoclonal Anti-Adenovirus 2 E1A (Adenovirus 2 early region 1) antibody produced in mouse

1.0 mg/mL, clone M73, purified immunoglobulin, buffered aqueous solution

• MDL-Nummer: MFCD00282028
• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: mouse
• Qualitätsniveau: 200
• Konjugat: unconjugated
• Antikörperform: purified immunoglobulin
• Antikörper-Produkttyp: primary antibodies
• Klon: M73, monoclonal
• Form: buffered aqueous solution
• Mol-Gew.: antigen 30-50 kDa (3 bands)
• Speziesreaktivität: viral
• Konzentration: 1.0 mg/mL
• Methode(n): immunoprecipitation (IP): 1-2 μg/mL using whole extract of HEK 293 cells; indirect immunofluorescence: 2-5 μg/mL
• Isotyp: IgG2a
• Versandbedingung: dry ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: unmodified

Beschreibung

Allgemeine Beschreibung

Adenovirus E1A gene modulates gene expression by associating with transcription factors in cells. Studies have reported that E1A regulates the stimulation of ICAM-1 through inflammatory signals in pulmonary epithelial cells. E1A has also been implicated in chronic obstructive pulmonary disease (COPD). Furthermore, E1A is known to mediate tumor suppression by rendering epithelial cells sensitive to anoikis. Mouse Monoclonal Anti-Adenovirus 2 E1A antibody binds to adenovirus 2 and 5 E1A (3 bands at 30-50kDa by SDS-PAGE), as well as E1A associated proteins.

Immunogen

full length recombinant adenovirus 2 E1A protein.

Anwendung

Monoclonal Anti-Adenovirus 2 E1A can be used for indirect immunofluorescence (2-5μg/mL) and immunoprecipitation (1-2μg/mL, using whole extract of HEK 293 cells).

Physikalische Form

Solution in phosphate buffered saline, pH 7.4, containing 0.08% sodium azide.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 13 - Non Combustible Solids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable