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Merck

A3626

Sigma-Aldrich

Nα-Acetyl-L-ornithin

≥98% (TLC), suitable for ligand binding assays

Synonym(e):

N2-acetyl-L-lysine

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About This Item

Empirische Formel (Hill-System):
C7H14N2O3
CAS-Nummer:
Molekulargewicht:
174.20
MDL-Nummer:
UNSPSC-Code:
12352202
eCl@ss:
32160406
PubChem Substanz-ID:
NACRES:
NA.26

product name

Nα-Acetyl-L-ornithin,

Assay

≥98% (TLC)

Form

powder

Methode(n)

ligand binding assay: suitable

Farbe

colorless to white

Lagertemp.

−20°C

SMILES String

CC(=O)N[C@@H](CCCN)C(O)=O

InChI

1S/C7H14N2O3/c1-5(10)9-6(7(11)12)3-2-4-8/h6H,2-4,8H2,1H3,(H,9,10)(H,11,12)/t6-/m0/s1

InChIKey

JRLGPAXAGHMNOL-LURJTMIESA-N

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Verwandte Kategorien

Biochem./physiol. Wirkung

Nα-Acetyl-L-ornithine (AORN) is a substrate for the identification, differentiation and characterization of N(α)-acetyl-L-ornithine deacetylase(s) and of N-Acetyl-l-ornithine transcarbamylase(s) (AOTCase) found in plants, some eubacteria and some human pathogens.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)


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N-Acetyl-l-ornithine transcarbamylase (AOTCase), rather than ornithine transcarbamylase (OTCase), is the essential carbamylase enzyme in the arginine biosynthesis of several plant and human pathogens. The specificity of this unique enzyme provides a potential target for controlling the spread of these pathogens.
Dashuang Shi et al.
Proteins, 64(2), 532-542 (2006-06-03)
N-acetyl-L-ornithine transcarbamoylase (AOTCase) is a new member of the transcarbamoylase superfamily that is essential for arginine biosynthesis in several eubacteria. We report here crystal structures of the binary complexes of AOTCase with its substrates, carbamoyl phosphate (CP) or N-acetyl-L-ornithine (AORN)
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