A3601

Anti-ADAM-19, N-Terminal antibody produced in rabbit

~1 mg/mL, affinity isolated antibody, buffered aqueous glycerol solution

• Synonym(e): Anti-A Disintegrin And Metalloproteinase-19, Anti-Meltrin-β
• MDL-Nummer: MFCD04040156
• UNSPSC-Code: 12352203

Eigenschaften

• Biologische Quelle: rabbit
• Konjugat: unconjugated
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous glycerol solution
• Speziesreaktivität: human
• Konzentration: ~1 mg/mL
• Methode(n): western blot: 1:1,000
• UniProt-Hinterlegungsnummer: Q9H013
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... ADAM19(8728)

Beschreibung

Allgemeine Beschreibung

ADAM19 or Meltrin-beta belongs to the ADAM (a disintegrin and metalloprotease-like domain) family. ADAM19 is found in muscle, bone, muscle, lung, heart, brain, kidney, and several other cells. This protein shares homology with the fertilins (ADAMs 1 and 2). Studies have reported that ADAM19 is involved in myoblast fusion, similar to sperm-egg fusion aided by ADAMs 1 and 2. Furthermore, ADAM19 has been implicated in osteoblast and dendritic cell differentiation, as well as in the intracellular processing of neuregulin.
Rabbit anti-ADAM-19, N-Terminal antibody localizes human ADAM19. By immunoblotting against the reduced protein, the antibody recognizes bands at 60kDa and 50kDa from cell lysates.

Immunogen

synthetic peptide corresponding to the N-terminal of furin-activated human ADAM-19.

Anwendung

Rabbit anti-ADAM-19, N-Terminal antibody can be used for western blot assays at a dilution of 1:1,000. It can also be used for chemiluminescent immunoassays at 1:5,000.

Physikalische Form

Solution in 0.01 M phosphate buffered saline containing 50% glycerol and 0.05% sodium azide.