A3097

[Pro¹⁸, Asp²¹]-Amyloid β Protein Fragment 17-21 trifluoroacetate salt

≥98% (HPLC), solid

• Empirische Formel (Hill-System): C₃₃H₄₃N₅O₈
• CAS-Nummer: 182912-74-9
• Molekulargewicht: 637.72
• MDL-Nummer: MFCD01862668
• UNSPSC-Code: 12352200

Eigenschaften

• Assay: ≥98% (HPLC)
• Form: solid
• UniProt-Hinterlegungsnummer: P05067
• Lagertemp.: −20°C
• SMILES String: CC(C)C[C@H](N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@@H](CC(O)=O)C(O)=O
• Angaben zum Gen: human ... APP(351)

Beschreibung

Amino Acid Sequence

Leu-Pro-Phe-Phe-Asp

Biochem./physiol. Wirkung

Inhibits amyloid formation in vitro and amyloid neurotoxicity in cell culture, reduces in vivo cerebral amyloid deposition and blocks amyloid fibrial formation in rat brain.

Inhibits amyloid formation in vitro, prevents amyloid neurotoxicity in cell culture, reduces in vivo cerebral amyloid deposition and completely blocks amyloid fibrial formation in rat brain.