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Merck

93658

Sigma-Aldrich

Esterase Pyrobaculum calidifontis, rekombinant

recombinant, expressed in E. coli, ≥2.0 U/mg

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About This Item

CAS-Nummer:
EC-Nummer:
EG-Nummer:
UNSPSC-Code:
12352204

Rekombinant

expressed in E. coli

Form

crystalline
crystals
powder or flakes

Spezifische Aktivität

≥2.0 U/mg

Lagertemp.

−20°C

Anwendung

Esterase, from Pyrobaculum calidifontis, may be used in structural biology research.

Biochem./physiol. Wirkung

An esterase is a hydrolase that splits esters into acids and alcohols.

Verpackung

Bottomless glass bottle. Contents are inside inserted fused cone.

Einheitendefinition

1 U corresponds to the amount of enzyme which converts 1 μmol 4-nitrophenyl-L-acetate per minute at pH 7.5 and 30°C.

Piktogramme

Health hazard

Signalwort

Danger

H-Sätze

Gefahreneinstufungen

Resp. Sens. 1

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Analysenzertifikate (COA)

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Gottfried J Palm et al.
Applied microbiology and biotechnology, 91(4), 1061-1072 (2011-05-27)
The highly thermostable esterase from the hyperthermophilic archaeon Pyrobaculum calidifontis VA1 (PestE) shows high enantioselectivity (E > 100) in the kinetic resolution of racemic chiral carboxylic acids, but little selectivity towards acetates of tertiary alcohols (E = 2-4). To explain
Marie C Fortin et al.
Drug metabolism and disposition: the biological fate of chemicals, 41(2), 326-331 (2012-12-12)
Studies on therapeutic drug disposition in humans have shown significant alterations as the result of pregnancy. However, it is not known whether pesticide metabolic capacity changes throughout pregnancy, which could affect exposure of the developing brain. We sought to determine
B Sànchez-Nogué et al.
Environmental science and pollution research international, 20(5), 3480-3488 (2012-12-06)
The common sole, Solea solea (Linneus, 1758), and the Senegalese sole, Solea senegalensis (Kaup, 1858), are two important commercial species that coexist in the NW Mediterranean. In order to assess the species' ability to respond to chemical insults, a comparison
Judit Marsillach et al.
Toxicology, 307, 46-54 (2012-12-25)
Exposure to organophosphorus (OP) compounds can lead to serious neurological damage or death. Following bioactivation by the liver cytochromes P450, the OP metabolites produced are potent inhibitors of serine active-site enzymes including esterases, proteases and lipases. OPs may form adducts
Joshua P Lewis et al.
Pharmacogenetics and genomics, 23(1), 1-8 (2012-11-01)
Carboxylesterase 1 (CES1) is the primary enzyme responsible for converting clopidogrel into biologically inactive carboxylic acid metabolites. We genotyped a functional variant in CES1, G143E, in participants of the Pharmacogenomics of Anti-Platelet Intervention (PAPI) study (n=566) and in 350 patients

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