73156

N-Methyl-L-serin

≥98% (TLC)

• Synonym(e): (S)-3-Hydroxy-2-(methylamino)-propionsäure, N-Me-Ser-OH
• Empirische Formel (Hill-System): C₄H₉NO₃
• CAS-Nummer: 2480-26-4
• Molekulargewicht: 119.12
• Beilstein: 2498641
• MDL-Nummer: MFCD00037756
• UNSPSC-Code: 12352202
• PubChem Substanz-ID: 329764666
• NACRES: NA.32

Eigenschaften

• Assay: ≥98% (TLC)
• Form: powder
• Optische Aktivität: [α]/D +9.5±1.0°, c = 1 in 1 M HCl
• Zusammensetzung: carbon, 39.5-41.1% ; nitrogen, 11.5-12.0%
• Farbe: white
• mp (Schmelzpunkt): 204 °C
• SMILES String: CN[C@@H](CO)C(O)=O
• InChI: 1S/C4H9NO3/c1-5-3(2-6)4(7)8/h3,5-6H,2H2,1H3,(H,7,8)/t3-/m0/s1
• InChIKey: PSFABYLDRXJYID-VKHMYHEASA-N

Beschreibung

Biochem./physiol. Wirkung

N-Methyl amino acids play an important role in investigations on prevention or therapy of Alzheimer′s disease, neurofibrillary tangles or amyloid plaque are physiological characteristics of this disease and ?-amyloid(40) fibrillogenesis and disassembly of ?-amyloid(40) fibrils is inhibited by short ?-amyloid congeners containing N-methyl amino acids at alternate residue. N-Methyl-L-serine stimulates hyaluronan production in human skin fibroblasts.

N-Methyl-L-serine has been found to stimulate production of high molecular mass hyaluronan in human fibroblasts. This effect was specific to methylated L-serine and not observed with other methylated amino acids.

Verpackung

Bottomless glass bottle. Contents are inside inserted fused cone.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable