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Merck

51431

Sigma-Aldrich

Atto Rho11-maleimid

BioReagent, suitable for fluorescence

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About This Item

UNSPSC-Code:
12352200
NACRES:
NA.32

Produktlinie

BioReagent

Form

solid

Hersteller/Markenname

ATTO-TEC GmbH

Fluoreszenz

λex 671 nm; λem 595 nm

Eignung

suitable for fluorescence

Lagertemp.

−20°C

Anwendung

Atto Rho11 maleimide is a new rhodamine dye featuring a functionality for coupling to bio-molecules such as DNA, RNA, proteins etc. The label shows very high fluorescence efficiency and exceptionally high photostability. The dye is moderately hydrophilic. ATTO Rho11 is a cationic dye. After coupling to a substrate the label carries a net electrical charge of +1. Maleimides are well suited for coupling to thiol groups. This is similar to iodacetamides, but maleimides react more selectively with thiols. They do not show significant reaction with histidine or methionine. Hydrolysis of maleimides to a mixture of isomeric nonreactive maleamic acids can compete significantly with thiol modification, particularly above pH 8. Maleimides may be used for labeling of amines, which usually requires a higher pH than reaction of maleimides with thiols.

Rechtliche Hinweise

This product is for Research use only. In case of intended commercialization, please contact the IP-holder (ATTO-TEC GmbH, Germany) for licensing.

Piktogramme

Exclamation mark

Signalwort

Warning

H-Sätze

Gefahreneinstufungen

Eye Irrit. 2 - Skin Irrit. 2

Lagerklassenschlüssel

13 - Non Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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Sun YQ, Liu J, Lv X, Liu Y, Zhao Y, Guo W.
Angewandte Chemie (Weinheim an der Bergstrasse, Germany), 51, 763407636-763407636 (2012)
Jan Klohs et al.
Basic research in cardiology, 103(2), 144-151 (2008-03-08)
Light in the near-infrared (NIR) region between 700-900 nm can penetrate deep into living tissue, thereby offering a unique opportunity to use near-infrared fluorescence (NIRF) imaging techniques to detect and visualize fluorescent probes in-vivo. In the past few years, many
Chunbai He et al.
Biomaterials, 33(33), 8569-8578 (2012-08-22)
Polymeric nanoparticles have been widely applied to oral delivery of protein drugs, however, few studies focused on the systematical elucidation of the size-dependent oral absorption mechanism with well-defined polymeric nanoparticles. Rhodamine B labeled carboxylated chitosan grafted nanoparticles (RhB-CCNP) with different
Jianghong Rao et al.
Current opinion in biotechnology, 18(1), 17-25 (2007-01-20)
In vivo fluorescence imaging uses a sensitive camera to detect fluorescence emission from fluorophores in whole-body living small animals. To overcome the photon attenuation in living tissue, fluorophores with long emission at the near-infrared (NIR) region are generally preferred, including

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