208R-1

GH (EP267) Rabbit Monoclonal Primary Antibody

• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100; 500
• Konjugat: unconjugated
• Antikörperform: culture supernatant
• Antikörper-Produkttyp: primary antibodies
• Klon: EP267, monoclonal
• Beschreibung: (For In Vitro Diagnostic Use in Select Regions (See Chart))
• Form: buffered aqueous solution
• Speziesreaktivität: human
• Verpackung: bottle of 1.0 mL predilute (208R-17); bottle of 7.0 mL predilute (208R-18); vial of 0.1 mL concentrate (208R-14); vial of 0.5 mL concentrate (208R-15); vial of 1.0 mL concentrate (208R-16)
• Hersteller/Markenname: Cell Marque^™
• Methode(n): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500
• Isotyp: IgG
• Versandbedingung: wet ice
• Lagertemp.: 2-8°C
• Angaben zum Gen: mouse ... Gh(14599)

Beschreibung

Allgemeine Beschreibung

Pituitary growth hormone (GH) plays a crucial role in stimulating and controlling the growth, metabolism and differentiation of many mammalian cell types by modulating the synthesis of multiple mRNA species. These effects are mediated by the binding of GH to its membrane-bound receptor, GHR, and involve a phosphorylation cascade that results in the modulation of numerous signaling pathways. GH is synthesized by acidophilic or somatotropic cells of the anterior pituitary gland. Human growth hormone contains 191 amino acid residues with two disulfide bridges. Anti-GH is a useful marker in classification of pituitary tumors and the study of pituitary disease (acromegaly).^1-3 It reacts with GH-producing cells. Growth hormone receptors have been found in various non-pituitary cells, including that from hepatocellular carcinoma and various benign and malignant cutaneous lesions.^4-6

Qualität

IVD

IVD

IVD

RUO

Verlinkung

GH Positive Control Slides, Product No. 208S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Physikalische Form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

Angaben zur Herstellung

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Sonstige Hinweise

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Rechtliche Hinweise

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany