07841

(R)-Mevalonsäure-5-phosphat Lithiumsalz

95% (TLC)

• Synonym(e): (R)-3-Hydroxy-3-methyl-5-phosphonooxy-pentansäure Lithiumsalz, (R)-5-Phospho-mevalonat Lithiumsalz, (R)-5-Phosphomevalonsäure Lithiumsalz
• Empirische Formel (Hill-System): C₆H₁₃O₇P · xLi⁺
• CAS-Nummer: 73566-35-5
• Molekulargewicht: 228.14 (free acid basis)
• UNSPSC Code: 12352106
• NACRES: NA.25
• Assay: 95% (TLC)

Eigenschaften

• Quality Segment: 100
• assay: 95% (TLC)
• optical activity: [α]/D -3.2±0.5°, c = 0.1 in 0.2 M HCl
• storage temp.: −20°C
• SMILES string: [P](=O)([O-])([O-])OCC[C@@](O)(CC(=O)[O-])C
• InChI: 1S/C6H13O7P/c1-6(9,4-5(7)8)2-3-13-14(10,11)12/h9H,2-4H2,1H3,(H,7,8)(H2,10,11,12)/p-3/t6-/m1/s1
• InChI key: OKZYCXHTTZZYSK-ZCFIWIBFSA-K

Beschreibung

Application

Mevalonic acid 5-phosphate (M5P) may be used as a reference material in assays for the separation or detection of mevalonic acid 5-phosphate. Mevalonic acid 5-phosphate is the immediate precursor of isopentenyl pyrophosphate (IPP) and the mevalonate pathway which leads to isoprenoid biosynthesis. Mevalonic acid 5-phosphate may be used as a substrate to identify and characterize phosphomevalonate kinase(s).

Biochem/physiol Actions

Metabolit des Mevalonatweges, der eine wichtige Rolle in der Biosynthese von Sterolen, Dolichol, Häm und Ubichinon spielt. Von Interesse für Forschungen im Bereich der Onkologie, Autoimmunkrankheiten, Arteriosklerose und Alzheimer-Krankheit, sowie für angeborenen Mangel an Mevalonatkinase.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable