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Merck

M9625

Sigma-Aldrich

L-Methionin

≥98% (HPLC)

Synonym(e):

(S)-2-Amino-4-methylmercapto-buttersäure, L-2-Amino-4-(methylthio)-buttersäure

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About This Item

Lineare Formel:
CH3SCH2CH2CH(NH2)CO2H
CAS-Nummer:
Molekulargewicht:
149.21
Beilstein:
1722294
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352209
eCl@ss:
32160406
PubChem Substanz-ID:
NACRES:
NA.26

product name

L-Methionin, reagent grade, ≥98% (HPLC)

Qualität

reagent grade

Qualitätsniveau

Assay

≥98% (HPLC)

Form

powder

Farbe

white

mp (Schmelzpunkt)

284 °C (dec.) (lit.)

Anwendung(en)

detection

SMILES String

CSCC[C@H](N)C(O)=O

InChI

1S/C5H11NO2S/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m0/s1

InChIKey

FFEARJCKVFRZRR-BYPYZUCNSA-N

Angaben zum Gen

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Anwendung

L-Methionine has been used in chloramine assay and malonaldehyde assay. It has also been used as a standard in methionine assay.

Biochem./physiol. Wirkung

L-Methionine serves as precursor for transmethylation and transsulphuration. Methionine adenosylation results in the formation of S-adenosyl-L-methionine (SAM). SAM serves as a methyl donor to a number of substances. This methylation is significantly associated with the immune system functioning. Thus, SAM deficiency causes severe combined immunodeficiencies. L-Methionine′s metabolic product, glutathione, is known to regulate immune response and has antiviral action.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)


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L-methionine as immune supportive supplement: a clinical evaluation
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Amino Acids (2006)
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The Journal of nutrition, 136(6 Suppl), 1682S-1693S (2006-05-17)
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Methionyl-tRNA synthetase (MARS) catalyzes the ligation of methionine to its cognate transfer RNA and therefore plays an essential role in protein biosynthesis. We used exome sequencing, aminoacylation assays, homology modeling, and immuno-isolation of transfected MARS to identify and characterize mutations

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