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B3022

Supelco

Beclomethasondipropionate

analytical standard, for drug analysis

Synonym(e):

9-Chlor-11β,17,21-trihydroxy-16β-methylpregna-1,4-dien-3,20-dion-17,21-dipropionat

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About This Item

Empirische Formel (Hill-System):
C28H37ClO7
CAS-Nummer:
5534-09-8
Molekulargewicht:
521.04
EG-Nummer:
226-886-0
MDL-Nummer:
MFCD00135613
UNSPSC-Code:
41116107
PubChem Substanz-ID:
329773210
NACRES:
NA.24

Qualität

analytical standard, for drug analysis

Qualitätsniveau

200

Assay

≥99%

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

Anwendung(en)

forensics and toxicology
veterinary

Format

neat

Lagertemp.

2-8°C

SMILES String

CCC(=O)OCC(=O)[C@@]1(OC(=O)CC)[C@@H](C)C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(Cl)[C@@H](O)C[C@]12C

InChI

1S/C28H37ClO7/c1-6-23(33)35-15-22(32)28(36-24(34)7-2)16(3)12-20-19-9-8-17-13-18(30)10-11-25(17,4)27(19,29)21(31)14-26(20,28)5/h10-11,13,16,19-21,31H,6-9,12,14-15H2,1-5H3/t16-,19-,20-,21-,25-,26-,27-,28-/m0/s1

InChIKey

KUVIULQEHSCUHY-XYWKZLDCSA-N

Angaben zum Gen

human ... NR3C1(2908)

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Allgemeine Beschreibung

Beclomethasone dipropionate belongs to the chemical class of chlorinated glucocorticoid diesters, well known for its use in the treatment of asthma due to its anti-inflammatory properties.

Anwendung

Beclomethasone dipropionate analytical standard can be used as follows:
  • Development of a reversed-phase high-performance liquid chromatographic (RP-HPLC) method, combined with UV detection to determine beclomethasone dipropionate in nanocapsule suspensions
  • Simultaneous determination of beclomethasone dipropionate and ketoconazole in their bulk and combined cream formulations using UV-spectrophotometry and RP-HPLC based methods
  • Estimation of beclomethasone dipropionate and formoterol fumarate in their combined dosage forms by stability indicating RP-HPLC method coupled with UV detection
  • Combined analysis of beclomethasone dipropionate and formoterol fumarate dihydrate using two UV-spectrometric and one RP-HPLC based methods in bulk and their pharmaceutical dosage forms
  • Multi-residue analysis of 21 glucocorticoids in environmental samples by ultra-high performance liquid chromatography (UHPLC) and mass spectrometry (MS)

Sonstige Hinweise

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Piktogramme

Health hazard
GHS08

Signalwort

Warning

H-Sätze

H361fd,H373

Gefahreneinstufungen

Repr. 2 - STOT RE 2

Zielorgane

Adrenal gland,Immune system,Bone

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

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Analysenzertifikate (COA)

Lot/Batch Number
0000399929
0000399934
0000388006
0000364585
0000364585

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Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 109(3), 185-189 (2012-08-28)
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