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B0600000

4-Amino-benzoesäure-ethylester

European Pharmacopoeia (EP) Reference Standard

Synonym(e):

Benzocain, Ethyl-4-amino-benzoat

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About This Item

Empirische Formel (Hill-System):
C9H11NO2
CAS-Nummer:
94-09-7
Molekulargewicht:
165.19
Beilstein:
638434
MDL-Nummer:
MFCD00007892
UNSPSC-Code:
41116107
PubChem Substanz-ID:
329773120
NACRES:
NA.24

Qualität

pharmaceutical primary standard

API-Familie

benzocaine

Hersteller/Markenname

EDQM

Anwendung(en)

pharmaceutical (small molecule)

Format

neat

Lagertemp.

2-8°C

SMILES String

CCOC(=O)c1ccc(N)cc1

InChI

1S/C9H11NO2/c1-2-12-9(11)7-3-5-8(10)6-4-7/h3-6H,2,10H2,1H3

InChIKey

BLFLLBZGZJTVJG-UHFFFAOYSA-N

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Allgemeine Beschreibung

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Anwendung

Benzocaine EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Verpackung

Dieses Produkt wird, wie von der entsprechenden Pharmakopöe geliefert, angeboten. Die aktuellen Mengeneinheiten finden Sie im Referenzsubstanzen-Katalog der EDQM.

Sonstige Hinweise

Sales restrictions may apply.

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Piktogramme

Exclamation mark
GHS07

Signalwort

Warning

H-Sätze

H317

Gefahreneinstufungen

Skin Sens. 1

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

233.6 °F

Flammpunkt (°C)

112 °C

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Analysenzertifikate (COA)

Lot/Batch Number

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Natriumsulfat ACS reagent, ≥99.0%, anhydrous, granular

Sigma-Aldrich

239313

Natriumsulfat

Wasserfreies Natriumsulfat United States Pharmacopeia (USP) Reference Standard

USP

1614807

Wasserfreies Natriumsulfat

9-Fluorenon 98%

Sigma-Aldrich

F1506

9-Fluorenon

Salzsäure 36.5-38.0%, BioReagent, for molecular biology

Sigma-Aldrich

H1758

Salzsäure

H A Cooper
Southern medical journal, 90(9), 946-948 (1997-09-26)
Acute methemoglobinemia is a medical emergency that can rapidly become fatal. A substantial number of drugs, including topical preparations, can precipitate this condition. I report a rare example of severe, acute methemoglobinemia caused by oropharyngeal anesthesia with topical benzocaine spray
L A Linares et al.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 18(3), 267-269 (1990-07-01)
Methemoglobinemia is a condition in which more than 2% of the hemoglobin of the blood has been oxidized to the ferric form, a molecule which is incapable of binding oxygen or carbon dioxide. Clinically, the patient appears lethargic, cyanotic, and
Methemoglobinemia: a complication after fiberoptic orotracheal intubation with benzocaine spray. A case report.
F D Ellis et al.
The Journal of bone and joint surgery. American volume, 77(6), 937-939 (1995-06-01)
L F Rodriguez et al.
The Annals of pharmacotherapy, 28(5), 643-649 (1994-05-01)
To report a case of benzocaine-induced inethemoglobinemia and present a review of the related literature. An 83-year-old man received benzocaine topical anesthesia 600 mg prior to intubation for resection of a thyroid adenoma. The patient became severely cyanotic after induction
Stephan Warnke et al.
Journal of the American Chemical Society, 137(12), 4236-4242 (2015-03-12)
The immediate environment of a molecule can have a profound influence on its properties. Benzocaine, the ethyl ester of para-aminobenzoic acid that finds an application as a local anesthetic, is found to adopt in its protonated form at least two
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