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Merck

91432

Supelco

Lauroyl-L-carnitin

analytical standard

Synonym(e):

(2R)-3-Carboxy-N,N,N-trimethyl-2-[(1-oxododecyl)-oxy]-1-propanaminium Inneres Salz, L-Carnitin-dodecanoylester, C12-Carnitine, Dodecanoyl-L-carnitin

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About This Item

Empirische Formel (Hill-System):
C19H37NO4
CAS-Nummer:
Molekulargewicht:
343.50
Beilstein:
4147610
UNSPSC-Code:
41116107
NACRES:
NA.24

Qualität

analytical standard

Qualitätsniveau

Assay

≥95.0% (HPLC)

Form

solid

Optische Aktivität

[α]/D -20.0±2.0°, c = 1 in methanol

Haltbarkeit

limited shelf life, expiry date on the label

Verunreinigungen

≤10.0% water

Anwendung(en)

clinical testing

Lagertemp.

2-8°C

SMILES String

C[N+](C)(C)C[C@H](OC(CCCCCCCCCCC)=O)CC([O-])=O

InChI

1S/C19H37NO4/c1-5-6-7-8-9-10-11-12-13-14-19(23)24-17(15-18(21)22)16-20(2,3)4/h17H,5-16H2,1-4H3/t17-/m1/s1

InChIKey

FUJLYHJROOYKRA-QGZVFWFLSA-N

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Allgemeine Beschreibung

Lauroyl-L-carnitine is a naturally occurring compound belonging to the acylcarnitine class of compounds, which are reported to be used as biomarkers in the diagnosis of carnitine deficiency.

Anwendung

Lauroyl-L-carnitine may be used as an analytical standard to determine the content of the analyte in maize plants using high-performance liquid chromatography coupled to triple quadrupole-liquid chromatography with tandem mass spectrometry (LC-MS/MS). The exogenous application of carnitine stimulates the transportation of fatty acids into mitochondria. The possible effect of carnitine on the lipid trafficking between cytoplasm, mitochondrial matrix and the mitochondrial respiration in the leaves of maize grown under normal and cold conditions is investigated. It may also be used as an analytical reference standard for the quantification of the analyte in human urine samples using liquid chromatography/electrospray ionization tandem mass spectrometry (LC/ESI-MS/MS).

Empfohlene Produkte

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Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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Exogenous carnitine application augments transport of fatty acids into mitochondria and stimulates mitochondrial respiration in maize seedlings grown under normal and cold conditions
Turk H, et al.
Cryobiology, 91, 97-103 (2019)
Matrix effect?corrected liquid chromatography/tandem mass-spectrometric method for determining acylcarnitines in human urine
Abe K, et al.
Clinica Chimica Acta; International Journal of Clinical Chemistry, 468, 187-194 (2017)

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