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Merck

89773

Supelco

Asiatsäure

analytical standard

Synonym(e):

2α,23-Dihydroxyursolsäure, NSC 166063

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About This Item

Empirische Formel (Hill-System):
C30H48O5
CAS-Nummer:
Molekulargewicht:
488.70
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
85151701
PubChem Substanz-ID:
NACRES:
NA.24

Qualität

analytical standard

Qualitätsniveau

Assay

≥95.0% (HPLC)

Haltbarkeit

limited shelf life, expiry date on the label

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

mp (Schmelzpunkt)

325-330 °C (lit.)

Anwendung(en)

food and beverages

Format

neat

SMILES String

C[C@@H]1CC[C@@]2(CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)C[C@@H](O)[C@H](O)[C@@](C)(CO)[C@@H]5CC[C@@]34C)[C@@H]2[C@H]1C)C(O)=O

InChI

1S/C30H48O5/c1-17-9-12-30(25(34)35)14-13-28(5)19(23(30)18(17)2)7-8-22-26(3)15-20(32)24(33)27(4,16-31)21(26)10-11-29(22,28)6/h7,17-18,20-24,31-33H,8-16H2,1-6H3,(H,34,35)/t17-,18+,20-,21-,22-,23+,24+,26+,27+,28-,29-,30+/m1/s1

InChIKey

JXSVIVRDWWRQRT-UYDOISQJSA-N

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Verwandte Kategorien

Anwendung

Asiatic acid (AA) has been used in a study to investigate its antihypertensive effect in high carbohydrate, high fat (HCHF) diet-induced MS metabolic syndrome (MS) rats. It has also been used in a study to understand its chemoprophylaxis effect against malaria in Sprague-Dawley rats.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Starting material for asiatic acid derivative synthesis for use as:
  • Anticancer agents
  • Glycogen phosphorylase inhibitors
  • Hepatoprotectants

Biochem./physiol. Wirkung

Asiatic acid is commonly used in wound healing. Asiatic acid has antioxidant, anti-inflammatory and neuroprotective properties.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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Analysenzertifikate (COA)

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Pre-infection administration of asiatic acid retards parasitaemia induction in Plasmodium berghei murine malaria infected Sprague-Dawley rats.
Mavondo GA, et al.
Malaria Journal, 15(1), 1-1 (2016)
Asiatic acid attenuates renin-angiotensin system activation and improves vascular function in high-carbohydrate, high-fat diet fed rats
Putcharawipa M, et al.
BMC Complementary and Alternative Medicine, 16(1), 1-1 (2016)
Wenjie Guo et al.
International immunopharmacology, 24(2), 232-238 (2014-12-20)
In the present study, the effect of asiatic acid, a natural triterpenoid compound, on murine experimental colitis induced by dextran sulfate sodium (DSS) and its possible mechanism were examined in vivo and vitro. Oral administration of asiatic acid dose-dependently attenuated
Yongfang Yuan et al.
Journal of ethnopharmacology, 163, 31-38 (2015-01-18)
Asiatic acid is one of the main components in the herb Centella asiatica, which is a well-known herbal medicine for its excellent pharmacological effects. To enhance the development potentials of asiatic acid as a chemopreventative agent, there is a great

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