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Merck

80621

Sigma-Aldrich

Piperazin

BioUltra, anhydrous, ≥99.0% (T)

Synonym(e):

1,4-Diazacyclohexan, Diethylendiamin

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About This Item

Empirische Formel (Hill-System):
C4H10N2
CAS-Nummer:
Molekulargewicht:
86.14
Beilstein:
102555
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12161700
eCl@ss:
39160301
PubChem Substanz-ID:
NACRES:
NA.25

Dampfdruck

0.8 mmHg ( 20 °C)

Qualitätsniveau

Produktlinie

BioUltra

Assay

≥99.0% (T)

Form

solid

Expl.-Gr.

14 %

Verunreinigungen

insoluble matter, passes filter test
≤1% water

pH-Wert

11.0-12.5 (25 °C, 0.1 M in H2O)

bp

145-146 °C (lit.)

mp (Schmelzpunkt)

109-112 °C (lit.)

Löslichkeit

H2O: 0.1 M at 20 °C, clear, colorless

Anionenspuren

chloride (Cl-): ≤50 mg/kg
sulfate (SO42-): ≤50 mg/kg

Kationenspuren

Al: ≤5 mg/kg
As: ≤0.1 mg/kg
Ba: ≤5 mg/kg
Bi: ≤5 mg/kg
Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤50 mg/kg
Li: ≤5 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Mo: ≤5 mg/kg
Na: ≤50 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Sr: ≤5 mg/kg
Zn: ≤5 mg/kg

λ

0.1 M in H2O

UV-Absorption

λ: 260 nm Amax: 0.035
λ: 280 nm Amax: 0.010

SMILES String

C1CNCCN1

InChI

1S/C4H10N2/c1-2-6-4-3-5-1/h5-6H,1-4H2

InChIKey

GLUUGHFHXGJENI-UHFFFAOYSA-N

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Signalwort

Danger

Gefahreneinstufungen

Eye Dam. 1 - Flam. Sol. 1 - Repr. 2 - Resp. Sens. 1B - Skin Corr. 1B - Skin Sens. 1B

Lagerklassenschlüssel

4.1B - Flammable solid hazardous materials

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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Mitsunori Kono et al.
Bioorganic & medicinal chemistry, 21(1), 28-41 (2012-12-12)
A series of piperazine ureas was designed, synthesized, and evaluated for their potential as novel orally available fatty acid amide hydrolase (FAAH) inhibitors that are therapeutically effective against pain. We carried out an optimization study of the lead compound 3
R A Lovell
The Veterinary clinics of North America. Small animal practice, 20(2), 453-468 (1990-03-01)
Review of all reports involving anthelmintics in dogs and cats to the IAPIC between January 1, 1986 and August 10, 1988, revealed that ivermectin (extra-label use) and piperazine accounted for over 50% of the calls assessed as toxicoses and suspected
Janie Sheridan et al.
Drug and alcohol review, 26(3), 335-343 (2007-04-25)
In this Harm Reduction Digest Sheridan, Butler, Wilkins and Russell address the emergent phenomenon of so-called 'legal party pills' which have become a significant drug issue in New Zealand and elsewhere. Although banned in a number of countries, they are
John A Christopher et al.
Journal of medicinal chemistry, 56(9), 3446-3455 (2013-03-23)
Biophysical fragment screening of a thermostabilized β1-adrenergic receptor (β1AR) using surface plasmon resonance (SPR) enabled the identification of moderate affinity, high ligand efficiency (LE) arylpiperazine hits 7 and 8. Subsequent hit to lead follow-up confirmed the activity of the chemotype
Julio H K Rozenfeld et al.
Biochimica et biophysica acta, 1848(1 Pt A), 127-133 (2014-10-16)
In this work, the bilayer structure of novel cationic lipid diC16-amidine was compared to the one of zwitterionic dipalmitoyl phosphatidylcholine ( DPPC), which shares the same hydrophobic domain. Differential scanning calorimetry shows that DPPC and diC16-am idine bilayers have similar

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