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Merck

75110

Supelco

Phyllanthin

analytical standard

Synonym(e):

(2S,3S)-(+)-1,4-Dimethoxy-2,3-diveratrylbutan

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About This Item

Empirische Formel (Hill-System):
C24H34O6
CAS-Nummer:
Molekulargewicht:
418.52
Beilstein:
2066503
MDL-Nummer:
UNSPSC-Code:
85151701
PubChem Substanz-ID:
NACRES:
NA.24

Qualität

analytical standard

Qualitätsniveau

Assay

≥95.0% (HPLC)

Haltbarkeit

limited shelf life, expiry date on the label

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

Anwendung(en)

food and beverages

Format

neat

SMILES String

COC[C@@H](Cc1ccc(OC)c(OC)c1)[C@@H](COC)Cc2ccc(OC)c(OC)c2

InChI

1S/C24H34O6/c1-25-15-19(11-17-7-9-21(27-3)23(13-17)29-5)20(16-26-2)12-18-8-10-22(28-4)24(14-18)30-6/h7-10,13-14,19-20H,11-12,15-16H2,1-6H3/t19-,20-/m1/s1

InChIKey

KFLQGJQSLUYUBF-WOJBJXKFSA-N

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Allgemeine Beschreibung

Phyllanthin is found in many Phyllanthus species. It is a lignan compound which exhibits various biochemical and pharmacological properties.

Anwendung

Phyllanthin may be used as a reference standard for the determination of the analyte in Phyllanthus species by high-performance thin layer chromatography (HPTLC).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Empfohlene Produkte

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Lagerklassenschlüssel

13 - Non Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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Analysenzertifikate (COA)

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Die Dokumentenbibliothek aufrufen

Protective activity of phyllanthin in ethanol-treated primary culture of rat hepatocytes.
Chirdchupunseree H and Pramyothin P
Journal of Ethnopharmacology, 128(1), 172- 176 (2010)
Quantitative determination of phyllanthin and hypophyllanthin in Phyllanthus species by high-performance thin layer chromatography.
Tripathi AK, et al.
Phytochemical Analysis, 17(6), 394- 397 (2006)
Phyllanthin from Phyllanthus amarus inhibits cellular and humoral immune responses in Balb/C mice.
Ilangkovan M, et al.
Phytomedicine, 23(12), 1441- 1450 (2016)
Cong Zhao et al.
Environmental toxicology (2020-08-17)
Ischemic heart disease is an imperative cause of high morbidity and mortality globally. The cardiac ischemia/reperfusion damage occur in both reperfusion and ischemia. In this exploration, we have planned to examine the cardio-protective action of phyllanthin against the myocardial ischemic-reperfusion
Nguyen Duc Hanh et al.
Drug development and industrial pharmacy, 40(6), 793-802 (2013-04-19)
Phyllanthin is a major bioactive lignan component of Phyllanthus amarus, with several known biological activities. This study dealt with the isolation and physicochemical characterization of phyllanthin. Phyllanthin was isolated from P. amarus leaves by column chromatography and purified by recrystallization

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