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Merck

198161

Sigma-Aldrich

Toluidinblau O

certified by the Biological Stain Commission

Synonym(e):

Bluten-chlorid, Methylen Blau T50 oder T extra, Rhodulinreinblau 17G, Tolonium-chlorid

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About This Item

Empirische Formel (Hill-System):
C15H16ClN3S
CAS-Nummer:
Molekulargewicht:
305.83
Farbindexnummer:
52040
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12171500
PubChem Substanz-ID:
NACRES:
NA.47

Qualität

certified by the Biological Stain Commission

Qualitätsniveau

Form

powder

Zusammensetzung

Dye content, 80%

Farbe

dark green

λmax

626 nm

ε (Extinktionskoeffizient)

≥13000 at 241-247 nm in H2O
≥28000 at 287-293 nm in H2O
≥40000 at 625-635 nm in H2O

Anwendung(en)

diagnostic assay manufacturing
hematology
histology

Lagertemp.

room temp

SMILES String

[Cl-].Cc1cc2N=C3C=CC(\C=C3Sc2cc1N)=[N+](\C)C

InChI

1S/C15H15N3S.ClH/c1-9-6-13-15(8-11(9)16)19-14-7-10(18(2)3)4-5-12(14)17-13;/h4-8,16H,1-3H3;1H

InChIKey

GEDVVYWLPUPJJZ-UHFFFAOYSA-N

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Allgemeine Beschreibung

Ein metachromatischer Farbstoff geeignet für eine Vielzahl von histologischen Färbungen.

Anwendung

Toluidine Blue O along with light-emitting diode has been used as a photosensitizer to control in vitro biofilms and to kill gram-negative bacteria.

Biochem./physiol. Wirkung

Toluidine Blue O (TBO) is a thiazine dye of the quinone-imine family and is cationic in nature. It has been employed in polychromatic staining of paraffin embedded plant cell walls. TBO can be removed from its aqueous solution by using an effective adsorbent, clinoptilolite. TBO and fixed output laboratory laser light source are used together to destroy variety of oral bacteria associated with dental caries. This metachromatic nuclear stain is often used in place of thionin or methylene blue. It also serves as a component of a tribasic stain along with Malachite Greenand Basic Fuchsin.

Eignung

Zertifiziert für den Einsatz in der metachromatischen Färbung von Mastzellen und Knorpel nach der Churukian-Schenk-Methode und der Nocht-Methode für Paraffinschnitte.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)


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Die Dokumentenbibliothek aufrufen

The Effect of Variable Energy Input from a Novel Light Source on the Photoactivated Bactericidal Action of Toluidine Blue O on Streptococcus mutans
Williams J A
Caries Research, 37, 190?193-190?193 (2003)
Polychromatic staining of plant cell walls by toluidine blue O
Brien T P O
Protoplasma, 59(2), 368- 373 (1964)
Anaīs Noblanc et al.
Antioxidants (Basel, Switzerland), 9(2) (2020-02-15)
There is growing evidence that the quality of spermatozoa decreases with age and that children of older fathers have a higher incidence of birth defects and genetic mutations. The free radical theory of aging proposes that changes with aging are
Photosensitization of in vitro biofilms by toluidine blue O combined with a light-emitting diode.
Zanin IC
European Journal of Oral Sciences, 114(1), 64-69 (2006)
Catherine White
Best practice & research. Clinical obstetrics & gynaecology, 27(1), 113-130 (2012-12-12)
The examination of the rape victim should focus on the therapeutic, forensic and psychological needs of the individual patient. One aspect will be an examination for ano-genital injuries. From a medical perspective, they tend to be minor and require little

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