178810-M

Tetrahydrofuran

≥99.0%, reagent grade, contains 250 ppm BHT as inhibitor

• Synonym(e): Butylenoxid, Oxolan, Tetramethylenoxid
• Empirische Formel (Hill-System): C₄H₈O
• CAS-Nummer: 109-99-9
• Molekulargewicht: 72.11
• Beilstein: 102391
• EG-Nummer: 203-726-8
• MDL-Nummer: MFCD00005356
• UNSPSC-Code: 12191501
• PubChem Substanz-ID: 329751576
• NACRES: NA.21

Eigenschaften

• product name: Tetrahydrofuran, reagent grade, ≥99.0%, contains 250 ppm BHT as inhibitor
• Qualität: reagent grade
• Dampfdichte: 2.5 (vs air)
• Dampfdruck: 114 mmHg ( 15 °C); 143 mmHg ( 20 °C)
• Assay: ≥99.0%
• Form: liquid
• Selbstzündungstemp.: 610 °F
• Enthält: 250 ppm BHT as inhibitor
• Expl.-Gr.: 1.8-11.8 %
• Brechungsindex: n20/D 1.407 (lit.)
• pH-Wert: ~7
• bp: 65-67 °C (lit.)
• mp (Schmelzpunkt): −108 °C (lit.)
• Dichte: 0.889 g/mL at 25 °C (lit.)
• SMILES String: C1CCOC1
• InChI: 1S/C4H8O/c1-2-4-5-3-1/h1-4H2
• InChIKey: WYURNTSHIVDZCO-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

Tetrahydrofuran (THF) is a saturated cyclic ether mainly used as an organic solvent. On long term storage it forms organic peroxides. This process can be suppressed by adding butylated hydroxytoluene (BHT) as a stabilizer. BHT removes the free radicals required for the peroxide formation. THF constitutes the key fragment of various natural products (polyether antibiotics). THF can form a double hydrate with hydrogen sulfide. Crystal structure of this double hydrate has been investigated by three-dimensional single-crystal studies. Butane-1,4-diol is formed as an intermediate during the synthesis of THF. Hot THF is useful for the dissolution of polyvinylidene chloride (PVDV).

Anwendung

Tetrahydrofuran may be used for the dissolution of poly-ε-caprolactone (PCL) and 1,3-diaminopentane, during the preparation of poly-ε-caprolactone (PCL)-hydroxyapatite (HA) scaffolds and acrylate-terminated poly(5-amino-1-pentanol-co-1,4-butanediol diacrylate) (C32)- 1,3-diaminopentane (117) polymer, respectively.

Sonstige Hinweise

For information on tetrahydrofuran miscibility, please visit the following link:
Tetrahydrofuran Miscibility/Immiscibility Table

Sicherheitshinweise

• Piktogramme: GHS02,GHS08,GHS07
• Signalwort: Danger
• H-Sätze: H225,H302,H319,H335,H336,H351
• P-Sätze: P202 - P210 - P233 - P301 + P312 - P305 + P351 + P338 - P308 + P313
• Gefahreneinstufungen: Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Zusätzliche Gefahrenhinweise: EUH019
• Lagerklassenschlüssel: 3 - Flammable liquids
• WGK: WGK 1
• Flammpunkt (°F): 1.4 °F - closed cup
• Flammpunkt (°C): -17.00 °C - closed cup