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114529

Sigma-Aldrich

Phenolrot

ACS reagent

Synonym(e):

Phenolsulfonphthalein

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About This Item

Empirische Formel (Hill-System):
C19H14O5S
CAS-Nummer:
143-74-8
Molekulargewicht:
354.38
Beilstein:
326470
EG-Nummer:
205-609-7
MDL-Nummer:
MFCD00003552
UNSPSC-Code:
12171500
PubChem Substanz-ID:
24847179
NACRES:
NA.47

Qualität

ACS reagent

Qualitätsniveau

200

Form

powder

Klarheit der Lösung

passes test

Methode(n)

titration: suitable

visual transition interval

6.8-8.2, yellow to red

Löslichkeit

water: 0.77 g/L at 100 °C

λmax

360 nm
557 nm (2nd)

ε (Extinktionskoeffizient)

≥10000 at 288-294 nm in H2O
≥55000 at 555-561 nm in H2O
≥7000 at 357-363 nm in H2O

Anwendung(en)

diagnostic assay manufacturing
hematology
histology

Lagertemp.

room temp

SMILES String

Oc1ccc(cc1)C2(OS(=O)(=O)c3ccccc23)c4ccc(O)cc4

InChI

1S/C19H14O5S/c20-15-9-5-13(6-10-15)19(14-7-11-16(21)12-8-14)17-3-1-2-4-18(17)25(22,23)24-19/h1-12,20-21H

InChIKey

BELBBZDIHDAJOR-UHFFFAOYSA-N

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Verwandte Kategorien

Allgemeine Beschreibung

Phenol Red is a phenolsulfonphthalein compound. It is present as a sulfonated hydroxyquinone in weakly acidic aqueous solutions. In alkaline solutions, the dye forms a hydrophilic dianion (a small, red anion that has a larger conjugated system than the yellow hydroxyquinone).

Anwendung

Phenol red is commonly used as a pH indicator in biology and medicine. It is incorporated into microbiological culture media for the identification of Escherichia coli strains. Its clinical diagnostic applications include the investigation of gastric and duodenal ulcers and the assessment of tear function in ophthalmology. Phenol red is also used as a tracer to assess the permeability of the ileal mucosal membrane and to assess bacterial leakage through root-filling materials in dentistry.
Phenol Red has been used for the preparation of phenol red gavage meal for measurement of gastric emptying in rats.
Geeignet als pH-Indikator

Biochem./physiol. Wirkung

Phenol Red is a pH indicator which changes color from yellow to red.

Piktogramme

Exclamation mark
GHS07

Signalwort

Warning

H-Sätze

H315,H335

Gefahreneinstufungen

Skin Irrit. 2 - STOT SE 3

Zielorgane

Respiratory system

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Gloves

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Analysenzertifikate (COA)

Lot/Batch Number
0000389289
0000389290
0000372792
0000372791
0000356118

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Van der Ploeg L, et al.
Life Sciences, 109, 20-29 (2014)
TiO2 nanotube arrays of 1000 ?m length by anodization of titanium foil: phenol red diffusion.
Paulose M, et al.
The Journal of Physical Chemistry C, 111, 14992-14997 (2007)
Shin-Nosuke Uno et al.
Nature chemistry, 6(8), 681-689 (2014-07-24)
Single-molecule localization microscopy is used to construct super-resolution images, but generally requires prior intense laser irradiation and in some cases additives, such as thiols, to induce on-off switching of fluorophores. These requirements limit the potential applications of this methodology. Here
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