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Merck

PC730

Anti-IDE, N-Terminal (97-273) Rabbit pAb

liquid, Calbiochem®

Synonym(e):

Anti-Insulin Degrading Enzyme, Anti-BC2

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Über diesen Artikel

NACRES:
NA.41
UNSPSC Code:
12352203
Clone:
polyclonal
Species reactivity:
rat, human, hamster, mouse
Application:
Citations:
22
Technischer Dienst
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biological source

rabbit

Quality Level

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

form

liquid

contains

≤0.1% sodium azide as preservative

species reactivity

rat, human, hamster, mouse

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze, avoid repeated freeze/thaw cycles

dilution

(ELISA (direct only) (1:2000-1:4000)
Immunoblotting (1:500-1:4000)
Immunocytochemistry (1:200-1:1000)
Immunoprecipitation (not recommended))

isotype

IgG

shipped in

wet ice

storage temp.

−70°C

target post-translational modification

unmodified

Gene Information

human ... IDE(3416)

General description

Rabbit polyclonal antibody supplied as undiluted serum. Recognizes the ~115 kDa endogenous as well as recombinant IDE protein.
Recognizes the ~115 kDa endogenous and recombinant IDE.
This Anti-IDE, N-Terminal (97-273) Rabbit pAb is validated for use in ELISA, Immunoblotting, Immunocytochemistry, Immunoprecipitation for the detection of IDE, N-Terminal (97-273).

Immunogen

Rat
a recombinant protein consisting of amino acids 97-273 of rat IDE fused to GST

Application

ELISA (direct only) (1:2000-1:4000)

Immunoblotting (1:500-1:4000)

Immunocytochemistry (1:200-1:1000)

Immunoprecipitation (not recommended)

Physical form

Undiluted serum.

Preparation Note

Following initial thaw, aliquot and freeze (-70°C).

Analysis Note

Positive Control
Rat or mouse liver cytosol

Other Notes

Antibody should be titrated for optimal results in individual systems.
Morelli, L., et al. 2003. J. Biol. Chem.278, 23221.
Kurochkin, I.V. and Goto, S. 1994. FEBS Lett.345, 33.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)


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Lagerklasse

10 - Combustible liquids

wgk

WGK 1



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Alzheimer's disease (AD) and vascular dementia (VaD) are the most common causes of dementia, and borderlines are blurred in many cases. Aging remains the main risk factor to suffer dementia; however, epidemiological studies reveal that diabetes may also predispose to
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The Journal of neuroscience : the official journal of the Society for Neuroscience, 32(49), 17824-17829 (2012-12-12)
Neuroinflammation plays a fundamental role in the pathogenesis of Alzheimer's disease (AD), resulting in the extensive activation of microglial and astroglial cells. Here we describe the role of myeloid-related protein Mrp14, a recently described amplifier of inflammation, in Alzheimer's disease
Xiqian Lan et al.
Journal of immunology (Baltimore, Md. : 1950), 186(12), 6925-6932 (2011-05-10)
The advent and wide introduction of antiretroviral therapy has greatly improved the survival and longevity of HIV-infected patients. Unfortunately, despite antiretroviral therapy treatment, these patients are still afflicted with many complications including cognitive dysfunction. There is a growing body of



Global Trade Item Number

SKUGTIN
PC730-100UL04055977207910