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Merck

MAB4343

Sigma-Aldrich

Anti-SOX-2 Antibody

clone 6F1.2, Chemicon®, from mouse

Synonym(e):

Anti-ANOP3, Anti-MCOPS3

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About This Item

UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Biologische Quelle

mouse

Qualitätsniveau

Antikörperform

purified immunoglobulin

Antikörper-Produkttyp

primary antibodies

Klon

6F1.2, monoclonal

Speziesreaktivität

mouse, human

Verpackung

antibody small pack of 25 μg

Hersteller/Markenname

Chemicon®

Methode(n)

immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable

Aufnahme

sample type: mouse embryonic stem cell(s)
sample type neural stem cell(s)
sample type: human embryonic stem cell(s)
sample type induced pluripotent stem cell(s)

Isotyp

IgG2b

NCBI-Hinterlegungsnummer

UniProt-Hinterlegungsnummer

Versandbedingung

ambient

Lagertemp.

2-8°C

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... SOX2(6657)
mouse ... Sox2(20674)

Allgemeine Beschreibung

Sox-2 plays a key role in embryonic stem cell development, and has been shown to help stem cells maintain pluripotent potential. It has also been shown to be associated with uncommitted dividing stem cell and precursor cells of the developing CNS.

Immunogen

Recombinant GST Fusion protein.

Anwendung

Research Category
Epigenetik & nukleäre Funktionen
Research Sub Category
Transkriptionsfaktoren
Anti-SOX-2 Antibody detects level of SOX-2 & has been published & validated for use in IC, IH & WB.

Qualität

Tested

Zielbeschreibung

~34 kDa

Physikalische Form

Format: Purified
Purified Immunoglobulin by protein A affinity chromatography and presented as a liquid in 0.02 M phosphate buffer, pH 7.6, with 0.25 M NaCl. Contains 0.1% sodium azide.

Lagerung und Haltbarkeit

Maintain refrigerated at 2-8°C in undiluted aliquots for up to 12 months.

Sonstige Hinweise

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Rechtliche Hinweise

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Die Dokumentenbibliothek aufrufen

Valentina Poletti et al.
PloS one, 10(5), e0126590-e0126590 (2015-05-16)
Genome-wide mapping of transcriptional regulatory elements is an essential tool for understanding the molecular events orchestrating self-renewal, commitment and differentiation of stem cells. We combined high-throughput identification of transcription start sites with genome-wide profiling of histones modifications to map active
Masoumeh Fakhr Taha et al.
BioMed research international, 2014, 941486-941486 (2014-08-26)
The expression pattern of pluripotency markers in adipose tissue-derived stem cells (ADSCs) is a subject of controversy. Moreover, there is no data about the signaling molecules that regulate these markers in ADSCs. In the present study, we studied the roles
High-content imaging-based screening of microenvironment-induced changes to stem cells.
Vega, SL; Liu, E; Patel, PJ; Kulesa, AB; Carlson, AL; Ma, Y; Becker, ML; Moghe, PV
Journal of Biomolecular Screening null
Weixiang Guo et al.
Nature protocols, 7(11), 2005-2012 (2012-10-20)
In adult mammals, the subventricular zone (SVZ) of the lateral ventricles and the subgranular zone of the dentate gyrus (DG) show ongoing neurogenesis, and multipotent neural stem or progenitor cells (NSCs) in these two regions exhibit different intrinsic properties. However
Olga Momčilović et al.
Stem cells and development, 23(4), 406-420 (2013-10-01)
Recent advances in human embryonic stem cell (ESC) and induced pluripotent stem cell (iPSC) biology enable generation of dopaminergic neurons for potential therapy and drug screening. However, our current understanding of molecular and cellular signaling that controls human dopaminergic development

Artikel

Skip weekend feedings. Defined serum-free and feeder-free expansion media for human pluripotent stem cells (ES and iPS cells). See publications and protocols.

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