CBL468
Anti-PECAM-1 Antibody, domains 3-6 of human PECAM-1, clone HC1/6
clone HC1/6, Chemicon®, from mouse
Synonym(e):
CD31
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About This Item
UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Empfohlene Produkte
Biologische Quelle
mouse
Qualitätsniveau
Antikörperform
purified immunoglobulin
Klon
HC1/6, monoclonal
Speziesreaktivität
human
Hersteller/Markenname
Chemicon®
Methode(n)
flow cytometry: suitable
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
immunoprecipitation (IP): suitable
Isotyp
IgG1
NCBI-Hinterlegungsnummer
UniProt-Hinterlegungsnummer
Versandbedingung
wet ice
Posttranslationale Modifikation Target
unmodified
Angaben zum Gen
human ... PECAM1(5175)
Spezifität
Reacts with a 130-140 kDa transmembranous glycoprotein that is expressed widely amongst cells of the vascular compartment. CD31 is expressed on platelets, cultured endothelial cells, monocytes, normal tissue macrophages in tonsil, lung and kidney as well as in skin biopsies from conditions such as sarcoidosis and lepromatous leprosy.
FUSION PARTNER: P3-x63Ag8.653 myeloma cell line
FUSION PARTNER: P3-x63Ag8.653 myeloma cell line
Immunogen
Epitope: domains 3-6 of human PECAM-1
Anwendung
Anti-PECAM-1 Antibody, domains 3-6 of human PECAM-1, clone HC1/6 is an antibody against PECAM-1 for use in FC, IH, IH(P) & IP.
Studies of the role of CD31 in leucocyte migration into inflammatory sites and in the process of angiogenesis
This antibody will stain frozen tissue sections
Suitable for immunoprecipitation studies
Suitable for flow cytometry either indirectly or directly when labelled with FITC or R-PE
Suitable for use on formalin fixed paraffin embedded sections after protease pre-treatment.
Optimal working dilutions must be determined by the end user.
This antibody will stain frozen tissue sections
Suitable for immunoprecipitation studies
Suitable for flow cytometry either indirectly or directly when labelled with FITC or R-PE
Suitable for use on formalin fixed paraffin embedded sections after protease pre-treatment.
Optimal working dilutions must be determined by the end user.
Physikalische Form
Format: Purified
Hinweis zur Analyse
Control
Activated microglial cells
Activated microglial cells
Sonstige Hinweise
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Rechtliche Hinweise
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Empfehlung
Produkt-Nr.
Beschreibung
Preisangaben
Lagerklassenschlüssel
10 - Combustible liquids
WGK
WGK 2
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
Analysenzertifikate (COA)
Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.
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Gina Lisignoli et al.
Journal of cellular physiology, 220(2), 401-409 (2009-04-15)
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Toxins, 14(2) (2022-02-25)
Shiga toxin-producing Escherichia coli (STEC) causes proximal tubular defects in the kidney. However, factors altered by Shiga toxin (Stx) within the proximal tubules are yet to be shown. We determined Stx receptor Gb3 in murine and human kidneys and confirmed
Yu-Ting Huang et al.
Cellular signalling, 20(8), 1521-1527 (2008-05-27)
Sphingosine 1-phosphate (S1P) is a multifunctional phospholipid which acts through a specific family of G protein-coupled receptors. Platelet/endothelial cell adhesion molecule-1 (PECAM-1) form trans-homophilic binding at lateral cell border. Upon stimulation, its cytoplasmic tyrosine residues could be phosphorylated and interact
Guiting Lin et al.
Stem cells and development, 17(6), 1053-1063 (2008-07-04)
Adipose tissue-derived stem cells (ADSC) are routinely isolated from the stromal vascular fraction (SVF) of homogenized adipose tissue. Freshly isolated ADSC display surface markers that differ from those of cultured ADSC, but both cell preparations are capable of multipotential differentiation.
Fumiko Obata et al.
The Journal of infectious diseases, 198(9), 1398-1406 (2008-08-30)
Affinity-purified Shiga toxin (Stx) 2 given intraperitoneally to mice caused weight loss and hind-limb paralysis followed by death. Globotriaosylceramide (Gb(3)), the receptor for Stx2, was localized to neurons of the central nervous system (CNS) of normal mice. Gb3 was not
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